DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CPD

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_196188.1	Gene:	CPD / 830453	AraportID:	AT5G05690	Length:	472	Species:	Arabidopsis thaliana

Alignment Length:	548	Identity:	135/548 - (24%)
Similarity:	218/548 - (39%)	Gaps:	132/548 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLGSSLLIGALWLLLRQLNKTYFILSLCKRVRTADGS---PLESKVFVVPG--KTRFGNNLDLLN 64
            ||.||:..|.|.||.|         :..:|:....||   ||..:.|.:.|  ||.        |
plant     8 LLLSSIAAGFLLLLRR---------TRYRRMGLPPGSLGLPLIGETFQLIGAYKTE--------N 55

  Fly    65 LTPANIFSYIRESTAKAN--------GQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYE 121
            ..|     :|.|..|:..        |:..|  |...||.|....::..::|:        .||.
plant    56 PEP-----FIDERVARYGSVFMTHLFGEPTI--FSADPETNRFVLQNEGKLFE--------CSYP 105

  Fly   122 L-IRPFLGDGLLISIDQKWHTRRKTLTPAF------------------HFNILQSFLS--IFKEE 165
            . |...||...|:.:....|.|..:||.:|                  .|| |.|:.|  :..||
plant   106 ASICNLLGKHSLLLMKGSLHKRMHSLTMSFANSSIIKDHLMLDIDRLVRFN-LDSWSSRVLLMEE 169

  Fly   166 SKKFIKILDKNVGFELELNQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCN 230
            :||        :.|||.:.|:               :..|........||   ::.:|.......
plant   170 AKK--------ITFELTVKQL---------------MSFDPGEWSESLRK---EYLLVIEGFFSL 208

  Fly   231 PLMFFNWYFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLA 295
            ||..|:      ..|:|..:..|.:....:.::.::|::         :|.|.:::..||..|||
plant   209 PLPLFS------TTYRKAIQARRKVAEALTVVVMKRREE---------EEEGAERKKDMLAALLA 258

  Fly   296 AEAEGKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLL-------LALHADVQERCYEELQDLPED 353
            |: :|..|.: |.|.:...:..||:||||  |.||.:       ||| |.::|. :|:::.:..|
plant   259 AD-DGFSDEE-IVDFLVALLVAGYETTST--IMTLAVKFLTETPLAL-AQLKEE-HEKIRAMKSD 317

  Fly   354 IDEVSMFQFNELIHLECVIKESLRLFPSAPIIG---RTCIEESVMNGLVLPKNAQISIHIYDIMR 415
            ...:....:..:...:||:.|:||:   |.|||   |..:.:..:.|..:||..::......:..
plant   318 SYSLEWSDYKSMPFTQCVVNETLRV---ANIIGGVFRRAMTDVEIKGYKIPKGWKVFSSFRAVHL 379

  Fly   416 DARHFPKPNQFLPERFLPENSVNRHPF-AFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLP 479
            |..||.....|.|.|: ..|||...|. .|.||..|||.|.|.:...:.:.|.|..::..|..:|
plant   380 DPNHFKDARTFNPWRW-QSNSVTTGPSNVFTPFGGGPRLCPGYELARVALSVFLHRLVTGFSWVP 443

  Fly   480 ATQLEDLTFENGIVLRTQQNIKVKFEAR 507
            |.|.:.:.|.   ..|||:...:..:.|
plant   444 AEQDKLVFFP---TTRTQKRYPIFVKRR 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	119/494 (24%)
CPD	NP_196188.1	p450	1..472	CDD:386267	135/548 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010