DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP702A3

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_193266.2	Gene:	CYP702A3 / 827197	AraportID:	AT4G15310	Length:	475	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	97/512 - (18%)
Similarity:	194/512 - (37%)	Gaps:	79/512 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LWLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRF---GNNLDLLNLTPANI----FS 72
            :::|...:..:..::.||..|........:.|  :.||...|   |...:.  :||.:|    ..
plant     4 IYVLALSVVFSLIVVKLCHWVYQWSNPKCKGK--LPPGSMGFPIIGETFEF--MTPFDISLVVSP 64

  Fly    73 YIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISIDQ 137
            |:::..:: .|.......||..:  ::.:.|.:...:..|.:::..:.|.:....|:.......:
plant    65 YLKKRISR-YGSKVFRTSLFGAK--VIVSIDPDVNMEIAKASSQLRATESVTRIFGENNPFLQSK 126

  Fly   138 KWHTRRKTLTPAFHFNILQSFLSIFKEESK-KFIKILDKNVGFELELNQIIPQFTLNNICETALG 201
            :.|...:.||..|          :..|..| :.|..:|..:..::|.......|.:.......:|
plant   127 EIHKYVRNLTSRF----------VGPEGLKTRLIHDIDNLLRNDVENGARNGSFDVREATIKMVG 181

  Fly   202 VKLDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNWYFF-----------LFGDYKKYSRILRTI 255
            ..:.....|....:|:.:.      .:|......:|:.|           |....:|.:::|:.:
plant   182 ELIAKKIMGETESEAVKEL------GLCWSAFRTSWFQFSYNIPGTTVYRLVKARRKAAKLLKAL 240

  Fly   256 HGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLL-AAEAEG-KIDHQGICDEVNTFMFGG 318
                  |:::|.   .::.||.           .||.:. ..|.:| .:|.....:.:..|....
plant   241 ------ILKKKA---SKEGLGD-----------FLDIIFDEMEKDGTALDIDKAVNLIFVFFILS 285

  Fly   319 YDTTSTSLIFTLLLLALHADVQERCYEE----LQDLPEDIDEVSMFQFNELIHLECVIKESLRLF 379
            .:||.......:.|:|.|..|.|....|    :|:..:....|:..::..:.....|||||||..
plant   286 QETTPGVQGAVVKLVADHPSVMEELQREHEAIVQNRADKDTGVTWEEYKSMTFTHMVIKESLRFT 350

  Fly   380 PSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQFLPERFLPE---NSVNRHP 441
            .:.|.:.|...::..:....||. ..:...|..:..|...:..|..|.|.|:..:   ::|:|.
plant   351 STQPTVHRIPDQDVQIGDYTLPA-GWLFFGIPQVHFDEEKYDDPLTFNPWRWQGKDINSTVSRE- 413

  Fly   442 FAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIR-NFKLLPATQL---EDLTFENGIVL 494
              ::||.||..:|:|.:|..|.|.:||..:.| .:.|.|.|::   ..|.|..|.|:
plant   414 --YMPFGAGGTHCVGSEFAKLIIAILLHHLSRFRWSLDPKTEVLRRYTLVFPAGCVV 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	92/476 (19%)
CYP702A3	NP_193266.2	p450	35..458	CDD:386267	89/469 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010