DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP72A15

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_001325567.1	Gene:	CYP72A15 / 820697	AraportID:	AT3G14690	Length:	547	Species:	Arabidopsis thaliana

Alignment Length:	487	Identity:	116/487 - (23%)
Similarity:	197/487 - (40%)	Gaps:	86/487 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLDLLNLTPANIFSYIRESTAKAN 82
            |:..|.|.:.:||      .|...||:....:.|....:          |..:|        |..
plant    87 LVGDLKKNFTMLS------EARSKPLKLTDDISPRVVPY----------PLQMF--------KTY 127

  Fly    83 GQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRP-------FLGDGLLISIDQKWH 140
            |:.|...|...|...|:..|..:|:|        |..|:..:|       .:..||......||.
plant   128 GRTYFTWFGPIPTITIMDPEQIKEVF--------NKVYDFQKPHTFPLATIIAKGLANYDGDKWA 184

  Fly   141 TRRKTLTPAFHFNILQSFLSIFKEESKKFI-----KILDKNVGFELELNQIIPQFTLNNICETAL 200
            ..|:.:.||||...:::.:..|.:..::.:     .:.||....|:::...:...|.:.|..||.
plant   185 KHRRIINPAFHIEKIKNMVPAFHQSCREVVGEWDQLVSDKGSSCEVDVWPGLVSMTADVISRTAF 249

  Fly   201 GVKLDDMSEGNEYRKAIHDFEI----------VFNQRMCNPLMFFNWYFFL-FGDYKKYSRILRT 254
                     |:.|::....||:          .|.:      .|...|.:| ....::.....|.
plant   250 ---------GSSYKEGQRIFELQAELAQLIIQAFRK------AFIPGYSYLPTKSNRRMKAAARE 299

  Fly   255 IHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAA---EAEGK-IDHQGICDEVNTFM 315
            |.....||:.::.         :..|.|:.....:|..||.:   :.||. :..:.:.:|...|.
plant   300 IQVILRGIVNKRL---------RAREAGEAPSDDLLGILLESNLRQTEGNGMSTEDLMEECKLFY 355

  Fly   316 FGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLPEDIDEVSMFQFNELIHLECVIKESLRLFP 380
            |.|.:|||..|::|::||:.|.|.|.|..||::.:..| .|......|:|..:..::.|.|||:|
plant   356 FAGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGD-KEPDAEGLNQLKVMTMILYEVLRLYP 419

  Fly   381 SAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPK-PNQFLPERFLPE-NSVNRHPFA 443
            ....:.|...:|..:..|.||...|||:.|..:..|...:.. ..:|.|:||... :...:...:
plant   420 PVTQLTRAIHKELKLGDLTLPGGVQISLPILLVQHDIELWGNDAAEFNPDRFKDGLSKATKSQVS 484

  Fly   444 FVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF 475
            |.||:.|||.||||.|.:||.|:.:|.::|.|
plant   485 FFPFAWGPRICIGQNFALLEAKMAMALILRRF 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	108/454 (24%)
CYP72A15	NP_001325567.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960