DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	118/491 - (24%)
Similarity:	215/491 - (43%)	Gaps:	47/491 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 WLLLRQLNKTYF---ILSLCKRVRTADGSPLE------SKVFVVPGKTRFGNNLDLL-NLTPANI 70
            |.:.|.|...:|   :|....|.:...|:|..      .|.|.:..:.| ...::|. ::|| .|
plant    19 WWVWRTLQWVWFKPKMLESYLRRQGLAGTPYTPLVGDLKKNFSMRAEAR-SKPINLTDDITP-RI 81

  Fly    71 FSYIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISI 135
            ..|..: ..|.:|:.:...|...|...|:..|...|:........|..::.|.| .:..|:|...
plant    82 VPYPLQ-MLKTHGRTFFTWFGAIPTITIMDPEQITEVLNKVYDFQKAHTFPLGR-LIATGVLSYD 144

  Fly   136 DQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFI-----KILDKNVGFELELNQIIPQFTLNNI 195
            ..||...|:.:.||||...:::.:..|.:...:.:     .:.||....|:::...:...|.:.|
plant   145 GDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESSCEVDVWPGLVSMTADVI 209

  Fly   196 CETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPL--MFFNWYFFL--FGDYKKYSRILRTIH 256
            ..||.|   ....||    :.|.:.:....|.:...:  .|...|.:|  .|:.:..:: .|.|.
plant   210 SRTAFG---SSCVEG----QRIFELQAELAQLIIQTVRKAFIPGYSYLPTKGNRRMKAK-AREIQ 266

  Fly   257 GFSSGIIQRKRQQFKQKQLGQV---DEFGKKQRYAMLDTLLAAEAEGKIDHQGICDEVNTFMFGG 318
            ....||:.::   .:.::.|:.   |..|     .:|::.|.......:..:.:.:|...|.|.|
plant   267 VILRGIVNKR---LRAREAGEAPNDDLLG-----ILLESNLGQTKGNGMSTEDLMEECKLFYFVG 323

  Fly   319 YDTTSTSLIFTLLLLALHADVQERCYEELQDLPEDIDEVSMFQFNELIHLECVIKESLRLFPSAP 383
            .:|||..|::|::||:.|.|.|.|..||::.:..| .|......|:|..:..::.|.|||:|..|
plant   324 QETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGD-KEPDAEGLNQLKVMTMILYEVLRLYPPIP 387

  Fly   384 IIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPK-PNQFLPERFLPE-NSVNRHPFAFVP 446
            .:.|...:|..:..|.||....|::.|..:.||...:.. ..:|.|:||... :...::..:|.|
plant   388 QLSRAIHKEMELGDLTLPGGVLINLPILLVQRDTELWGNDAGEFKPDRFKDGLSKATKNQASFFP 452

  Fly   447 FSAGPRNCIGQKFGVLEIKVLLAAVIR--NFKLLPA 480
            |:.|.|.||||.|.:||.|:.:|.:::  :|:|.|:
plant   453 FAWGSRICIGQNFALLEAKMAMALILQRFSFELSPS 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	108/447 (24%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	116/486 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960