Protein Alignment Cyp4ac3 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001003947.1
• Gene: Cyp4x1 / 81906
• MGIID: 1932403
• Length: 507
• Species: Mus musculus
• Alignment Length: 538
• Identity: 157/538 - (29%)
• Similarity: 248/538 - (46%)
• Gaps: 106/538 - (19%)

  Fly    11 LIGALWLLLRQLNKTYFILSLCKRVR-TADGSPLESKVFVVP------GKTRF--GNNLDLLN-- 64
            |:..|.|:|.|..|.|.     :|.| ..|.||     |..|      |..:|  .:|::.|:
Mouse    18 LVFCLALVLMQAMKLYL-----RRQRLLRDLSP-----FPGPPAHWLLGHQKFLQEDNMETLDEI 72

  Fly    65 -----------LTPANIFSYIRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNM 118
                       :.|...|.||                 :.|:|        .:||.|.  |...|
Mouse    73 VKKHPCAFPCWVGPFQAFFYI-----------------YDPDY--------AKIFLSR--TDPKM 110

  Fly   119 SY--ELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKILDKNVGFE- 180
            .|  :|:.|.:|.|||.....:|...|..||||||.:||:..:.......|   .:|||   :|
Mouse   111 QYLHQLLTPCIGRGLLNLDGPRWFQHRCLLTPAFHQDILKPCVDTMAHSVK---VMLDK---WEK 169

  Fly   181 --------LELNQIIPQFTLNNICETALGVKLDDMSEG--NEYRKAIHDFEIVFNQRMCNPLMFF 235
                    :|:.:.|...||:.|.:.|.|.:.:....|  ..|.||..:...:.:.|:.|   |:
Mouse   170 MWTTQETTIEVFEHINLMTLDIIMKCAFGQETNCQINGTYESYVKATFELGEIISSRLYN---FW 231

  Fly   236 NWYFFLFGDYKK---YSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAE 297
            :.:..:|....|   :..:.:.||.::..|||.:::..|    .||.:...:.....||.:|:|:
Mouse   232 HHHDIIFKLSPKGHCFQELGKVIHQYTEKIIQDRKKILK----NQVKQDDTQTSQIFLDIVLSAQ 292

  Fly   298 AEGKIDHQGICD-----EVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLPEDIDEV 357
            ||   |.:...|     ||||||:.|:|.::.|:.:.|..|||:.:.|:||..|::.:..|...:
Mouse   293 AE---DERAFSDADLRAEVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGDGSSI 354

  Fly   358 SMFQFNELIHLECVIKESLRLFPSAPIIGRTCIEE-SVMNGLVLPKNAQISIHIYDIMRDARHFP 421
            :..|.:|:.:....|||:|||.|..|.|.|...:. ::.:|..||....:.:.|:.:..:...:.
Mouse   355 TWEQLDEMSYTTMCIKETLRLIPPVPSISRELSKPLTLPDGHSLPAGMTVVLSIWGLHHNPAVWN 419

  Fly   422 KPNQFLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLEDL 486
            .|..|.|.||..|||..|||.||:|||:||||||||:|.:||:||.:|.::.:|::.|     ||
Mouse   420 DPKVFDPLRFTKENSDQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALILLHFQVAP-----DL 479

  Fly   487 T----FENGIVLRTQQNI 500
            |    |.:..|||.:..|
Mouse   480 TRPPAFSSHTVLRPKHGI 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	135/440 (31%)
Cyp4x1	NP_001003947.1	CYP4B-like	66..500	CDD:410771	140/480 (29%)