DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac3 and CYP96A1

DIOPT Version :9

Sequence 1:	NP_608918.1	Gene:	Cyp4ac3 / 33756	FlyBaseID:	FBgn0031695	Length:	509	Species:	Drosophila melanogaster
Sequence 2:	NP_179899.1	Gene:	CYP96A1 / 816850	AraportID:	AT2G23180	Length:	516	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	120/531 - (22%)
Similarity:	220/531 - (41%)	Gaps:	93/531 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IGALWLLLRQLNKTY-FILSLCKRVRTADGSPLESKVFVVPGKTRFGNNLD-LLNLTPANIFSYI 74
            :|.|..||.::.:.| |:..|           ||:.....|.|......|| |:.:.||||...:
plant    40 LGMLPGLLVEIPRVYDFVTEL-----------LEASNLTYPFKGPCFGGLDMLITVDPANIHHIM 93

  Fly    75 RESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELIRPFLGDGLLISIDQKW 139
                 .:|..||                            .|...::.|...||||:..:..:.|
plant    94 -----SSNFANY----------------------------PKGTEFKKIFDVLGDGIFNADSELW 125

  Fly   140 HTRRKTLTPAFHFNILQSFL--SIFKEESKKFIKILD-----KNVGFELELNQIIPQFTLNNICE 197
            ...||:..........|.|.  :|..:..|..:.:||     |.|   ::|..:..:||.:....
plant   126 KDLRKSAQSMMTHQDFQRFTLRTIMSKLEKGLVPLLDYVAEKKQV---VDLQDVFQRFTFDTSFV 187

  Fly   198 TALGVK---LDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNWYFFL-FGDYKKYSRILRTIHGF 258
            .|.||.   |.......|:.:|:.:.|.....|...|.:.:....|: |||..|..:...|....
plant   188 LATGVDPGCLSTEMPQIEFARALDEAEEAIFFRHVKPEIVWKMQRFIGFGDELKMKKAHSTFDRV 252

  Fly   259 SSGIIQRKRQQFKQKQLGQVDEFGKK--QRYAMLDTLLAAEAEGKI----DHQGICDEVNTFMFG 317
            .|..|..||.:.....: .:|...|.  ..|..:|| :....:.|:    |.:.:.|.:.:||..
plant   253 CSKCIASKRDEITNGVI-NIDSSSKDLLMCYMNVDT-ICHTTKYKLLNPSDDKFLRDMILSFMLA 315

  Fly   318 GYDTTSTSLIFTLLLLALH----ADVQERCYEELQDLPEDIDEVSMFQFNELIHLECVIKESLRL 378
            |.||||::|.:...||:.:    ..:::....:|.....|.|..:..:.|:|:::...:.|:|||
plant   316 GRDTTSSALTWFFWLLSKNPKAITKIRQEINTQLSPRTNDFDSFNAQELNKLVYVHGALCEALRL 380

  Fly   379 FPSAPIIGRTCIEESVM-NGLVLPKNAQISIHIYDIMR-------DARHFPKPNQFLPERFLPEN 435
            :|..|...::..:..|: :|..:..:::|...:|.:.|       ||      ::|.|||::.|:
plant   381 YPPVPFQHKSPTKSDVLPSGHRVDASSKIVFCLYSLGRMKSVWGEDA------SEFKPERWISES 439

  Fly   436 S--VNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNF--KLLPATQLEDLTFENGIVLRT 496
            .  ::...|.|:.|:||||.|:|::..:.::|.:...:|:|:  |::...::|.:.   .|:|..
plant   440 GRLIHVPSFKFLSFNAGPRTCLGKEVAMTQMKTVAVKIIQNYEIKVVEGHKIEPVP---SIILHM 501

  Fly   497 QQNIKVKFEAR 507
            :..:||....|
plant   502 KHGLKVTVTKR 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	p450	51..504	CDD:278495	110/486 (23%)
CYP96A1	NP_179899.1	p450	1..512	CDD:299894	119/529 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	151	1.000	Domainoid score	I1385
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920