Protein Alignment Cyp4ac3 and cyp11a1.2

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_691817.1
• Gene: cyp11a1.2 / 563363
• ZFINID: ZDB-GENE-130911-1
• Length: 512
• Species: Danio rerio
• Alignment Length: 497
• Identity: 112/497 - (22%)
• Similarity: 204/497 - (41%)
• Gaps: 119/497 - (23%)

  Fly    50 VPGKTRFGNNLDLLNLTPANIFSYIRESTAKANGQNYIWNF-LFAPEY----------NIVRAED 103
            :||:.|  |:|       .::|::.:....:...:..:.|| .|.|.|          ||::.||
Zfish    47 IPGQWR--NSL-------KSVFAFAKMGGLRNIHRIMVHNFNTFGPIYREKVGFYESVNIIKPED 102

  Fly   104 AEEIFQS-----TKITT---------KNMSYELIRPFLGDGLLISIDQKWHTRR-----KTLTPA 149
            |..:|::     .::|.         :|..|         |:|:...:.|.:.|     :.::|.
Zfish   103 AAILFKAEGHYPKRLTIDAWTAYRDYRNRKY---------GVLLKDGEDWKSNRIILNKEVISPK 158

  Fly   150 FHFNILQSFLSIFKEESKKFIKILDKNV------GFELELNQIIPQFTLNNICETALGVKLDDMS 208
            ...|    |:.:..|..:.|:..::|.:      .:..:|:..:.:|.|.::.....|.:|.
Zfish   159 VQGN----FVPLLDEVGQDFVARVNKKIERSGQNQWTTDLSHELFKFALESVSAVLYGERLG--- 216

  Fly   209 EGNEYRKAIHDFEIVFNQRM--CNPLMFFNWYFFLF----------------------GDYKKYS 249
                   .:.|:....:||.  |..|||......|:                      |.:.:..
Zfish   217 -------LLLDYIDPDSQRFIDCITLMFKTTSPMLYLPPGLLRPIRSKIWRNHVEAWDGIFNQAD 274

  Fly   250 RILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEAEGKIDHQGICDEVNTF 314
            |.::.|:           :|.::...|.....|......|||         |:..:.|...|...
Zfish   275 RCIQNIY-----------RQLRKNPEGNGKYTGVLASLLMLD---------KLSIEDIKASVTEL 319

  Fly   315 MFGGYDTTSTSLIFTLLLLALHADVQERCYEELQ--DLPEDIDEVSMFQFNELIHLECVIKESLR 377
            |.||.|||:.:|::||..||.:.|:||....|:.  .:....|.|.|.:...|:  :..:||:||
Zfish   320 MAGGVDTTAITLLWTLYELARNPDLQEEIRAEISAARIASKGDMVQMLKMIPLV--KGTLKETLR 382

  Fly   378 LFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQFLPERFLPENSVNRHPF 442
            |.|.|..:.|...|:.|:....:|....:.:.:|.:.||.:.||.|.|:||.|::  ||.| |.|
Zfish   383 LHPVAVSLQRYITEDIVIQKYHIPAGTLVQLGLYAMGRDHQVFPNPEQYLPSRWV--NSQN-HYF 444

  Fly   443 AFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLE 484
            ..:.|..|||.|:|::....|:::.|..::.||::....|:|
Zfish   445 KSLSFGFGPRQCLGRRIAETEMQLFLIHMLENFRIEKQRQME 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	106/460 (23%)
cyp11a1.2	XP_691817.1	cytochrome_P450	78..501	CDD:477761	105/457 (23%)