Protein Alignment Cyp4ac3 and cyp2a6.8

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001010999.1
• Gene: cyp2a6.8 / 496408
• XenbaseID: XB-GENE-5806705
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 551
• Identity: 128/551 - (23%)
• Similarity: 225/551 - (40%)
• Gaps: 114/551 - (20%)

  Fly     1 MW---IALLGSSLLIGALWLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKT---RFGNN 59
            :|   :.||.:::||.:.|      ||.|       |.|.           :.||.|   .|||
 Frog     6 LWSLQLFLLIATMLIYSTW------NKMY-------RKRN-----------LPPGPTPIPLFGN- 45

  Fly    60 LDLLNLTPANIFSYIRESTAKANGQNY--IWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYEL 122
              :|.:....:...:.|.     |:.|  ::...|.|...|:..:     :||.|....:.:.|
 Frog    46 --VLQIKRGEMVKSLLEL-----GKKYGPVYTLYFGPSPVIILCD-----YQSIKEALNDQAEE- 97

  Fly   123 IRPFLGDGLLISIDQ-------------KW-HTRRKTLTPAFHFNI-LQSFLSIFKEESKKFIKI 172
               |.|.|.:.|.||             :| ..||.:||...:|.: .:......:||::..:..
 Frog    98 ---FSGRGKIPSWDQFFQGYGESFSNGDEWKQLRRFSLTTLRNFGMGKRGIEERIQEEAQFLVAE 159

  Fly   173 LDKNVGFELELNQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEIVF--NQRMCNPLMFF 235
            :....|...:..:|:.|...|.||....|.:.:  ....::.|.::.|:.||  .......||..
 Frog   160 IKSYKGKPFDPTKILVQCVSNVICSVVFGQRYE--YSNKDFHKLLYMFQAVFEDTSSTLGQLMTL 222

  Fly   236 --NWYFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEA 298
              |....:.|.:|.....|..::.|   |:||.::..|.........|        :|:.|....
 Frog   223 LPNIMNHIPGPHKTVVNKLNKVNDF---ILQRVKENEKTLDPNSPRHF--------IDSFLIQMQ 276

  Fly   299 EGKID-------HQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEEL-----QDLP 351
            :.|.:       ...:|..:|.| |.|.:|.||:|....|:|.:|.:::|:.:||:     ||..
 Frog   277 KEKDNPVTKFHWKNLLCTIMNLF-FAGTETVSTTLRHGFLMLLIHPEIEEKLHEEIDRVVGQDRS 340

  Fly   352 EDIDEVSMFQFNELIHLECVIKESLRLFPSAPI-IGRTCIEESVMNGLVLPKNAQISIHIYDIMR 415
            ..|::.|     ::.:.:.||.|..|.....|: :....::::...|..:||...:...|...:|
 Frog   341 PTIEDRS-----KMPYTDAVIHEIQRFSDVLPMSLPHLVMKDTQFRGYTIPKGTDVYPLICAALR 400

  Fly   416 DARHFPKPNQFLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPA 480
            |.:.|..||:|.|:.||.:|.:.:...||:|||.|.|.|:|:....:|:.:.|..:::||||...
 Frog   401 DPKQFATPNKFNPQHFLDDNGLFKSSNAFLPFSTGKRICLGEGLARMELFLFLTNILQNFKLHSE 465

  Fly   481 TQL-ED-------------LTFENGIVLRTQ 497
            .|. ||             |::|..::.|.|
 Frog   466 NQFAEDDIAPKMNGFANYPLSYEFSLIPRVQ 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	107/457 (23%)
cyp2a6.8	NP_001010999.1	CYP2	65..488	CDD:410652	105/450 (23%)