Protein Alignment Cyp4ac3 and Cyp4f5

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_775147.1
• Gene: Cyp4f5 / 286905
• RGDID: 708364
• Length: 526
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 167/561 - (29%)
• Similarity: 265/561 - (47%)
• Gaps: 109/561 - (19%)

  Fly     2 WIAL----LGS-------SLLIGAL-WLLLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKT 54
            |:.:    |||       .||:||. |:|.|.|..||.....|.|:|....||
  Rat     3 WLTVSGLDLGSVVTSTWHLLLLGAASWILARILAWTYSFCENCSRLRCFPQSP------------ 55

  Fly    55 RFGNNLDLLNLTPANIFSYIRESTAKAN----------GQNY-----IWNFLFAPEYNIVRAED- 103
              ..|..|.:|           .|.::|          ||.:     .|   ..|...::|..|
  Rat    56 --KRNWFLGHL-----------GTIQSNEEGMRLVTEMGQTFRDIHLCW---LGPVIPVLRLVDP 104

  Fly   104 ---AEEIFQSTKITTKNMSY-ELIRPFLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKE 164
               |..:.....:..|:.:: ..::|:|||||.:|...||...|:.|||||||:||:.::.||.:
  Rat   105 AFVAPLLQAPALVAPKDTTFLRFLKPWLGDGLFLSSGDKWSRHRRLLTPAFHFDILKPYVKIFNQ 169

  Fly   165 ESKKFIKILD---KNVGFE----LELNQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEI 222
            .    :.|:.   |::..|    ||:.:.|...||:::.:...|...:.....:||..||.:...
  Rat   170 S----VNIMHAKWKHLCLEGSARLEMFENISLMTLDSLQKCLFGFDSNCQESPSEYISAILELSS 230

  Fly   223 VFNQRMCNPLMFFNWYFFLFGDYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLGQVDEF------ 281
            :..:|.....::.::.::...|.:::.:....:|.|:..:|:.:|:....:   ..|||
  Rat   231 LIIKRSQQLFLYLDFLYYRTADGRRFRKACDLVHNFTDAVIRERRRLLSSQ---GTDEFLESKTK 292

  Fly   282 GKKQRYAMLDTLLAAEAE-GK-IDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCY 344
            .|.:....:|.||.|:.| || :..:.|..|.:||||||:|||:::|.:.|..||.|.:.||||.
  Rat   293 SKSKTLDFIDVLLLAKDEHGKELSDEDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCR 357

  Fly   345 EELQDL-----PEDI--DEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIEESVM-NGLVLP 401
            :|:.:|     ||:|  |:::...|     |...|||||||.|.|..:.|.|.::.|: :|.|:|
  Rat   358 QEVWELLRDREPEEIEWDDLAQLPF-----LTMCIKESLRLHPPAIDLLRRCTQDIVLPDGRVIP 417

  Fly   402 KNAQISIHIYDIMRDARHFPKPNQFLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKV 466
            |.....|.|:.|..:...:|.|..|.|.||..||...|.|.:|:||||||||||||.|.:.|:||
  Rat   418 KGNICVISIFGIHHNPSVWPDPEVFDPFRFDSENRQKRSPLSFIPFSAGPRNCIGQTFAMNEMKV 482

  Fly   467 LLAAVIRNFKLLPATQLED----------LTFENGIVLRTQ 497
            ::|..:..|::||    :|          |..|.|:.||.:
  Rat   483 VVALTLLRFRVLP----DDKEPRRKPEIILRAEGGLWLRME 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	141/449 (31%)
Cyp4f5	NP_775147.1	CYP4F	74..517	CDD:410772	141/461 (31%)