Protein Alignment Cyp4ac3 and CYP26A1

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_000774.2
• Gene: CYP26A1 / 1592
• HGNCID: 2603
• Length: 497
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 86/374 - (22%)
• Similarity: 165/374 - (44%)
• Gaps: 49/374 - (13%)

  Fly   123 IRPFLGDGLLISIDQKWH-TRRKTLTPAFHFNILQSFLSIFKEE----SKKFIKILDKNVGFELE 182
            :|..||.|.|.::....| .|:|.:..||....|:.::.:..||    .::::...::.:....|
Human   116 VRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPE 180

  Fly   183 LNQIIPQFTLNNI--CETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPL--MFFNWYFFLFG 243
            :.:::.:..:..:  ||..|.      .:|:..::.:..||.:.......|:  .|...|
Human   181 VKRLMFRIAMRILLGCEPQLA------GDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLY----- 234

  Fly   244 DYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLG-QVDEFGKKQRYAMLDTLL--AAEAEGKIDHQ 305
               :..:....||.       |..|..:.|..| :..|.|:..:.| |..|:  :.|...::|.|
Human   235 ---RGMKARNLIHA-------RIEQNIRAKICGLRASEAGQGCKDA-LQLLIEHSWERGERLDMQ 288

  Fly   306 GICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEEL----------QDLPEDIDEVSMF 360
            .:.......:|||::||:::....:..|.|:..|.::..|||          ||     :::.|.
Human   289 ALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD-----NKLDME 348

  Fly   361 QFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQ 425
            ...:|.::.|||||:|||.|..|...|..::...:||..:||...:...|.|....|..|....:
Human   349 ILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 413

  Fly   426 FLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRN 474
            |.|:||:..:..:...|:|:||..|.|:|:|::|..:.:|:....:.|:
Human   414 FNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	86/374 (23%)
CYP26A1	NP_000774.2	CYP26A1	55..490	CDD:410731	86/374 (23%)