DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cyp4ac3 and CYP26A1

DIOPT Version :9

Sequence 1:NP_608918.1 Gene:Cyp4ac3 / 33756 FlyBaseID:FBgn0031695 Length:509 Species:Drosophila melanogaster
Sequence 2:NP_000774.2 Gene:CYP26A1 / 1592 HGNCID:2603 Length:497 Species:Homo sapiens


Alignment Length:374 Identity:86/374 - (22%)
Similarity:165/374 - (44%) Gaps:49/374 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 IRPFLGDGLLISIDQKWH-TRRKTLTPAFHFNILQSFLSIFKEE----SKKFIKILDKNVGFELE 182
            :|..||.|.|.::....| .|:|.:..||....|:.::.:..||    .::::...::.:....|
Human   116 VRTILGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLSCGERGLLVYPE 180

  Fly   183 LNQIIPQFTLNNI--CETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPL--MFFNWYFFLFG 243
            :.:::.:..:..:  ||..|.      .:|:..::.:..||.:.......|:  .|...|     
Human   181 VKRLMFRIAMRILLGCEPQLA------GDGDSEQQLVEAFEEMTRNLFSLPIDVPFSGLY----- 234

  Fly   244 DYKKYSRILRTIHGFSSGIIQRKRQQFKQKQLG-QVDEFGKKQRYAMLDTLL--AAEAEGKIDHQ 305
               :..:....||.       |..|..:.|..| :..|.|:..:.| |..|:  :.|...::|.|
Human   235 ---RGMKARNLIHA-------RIEQNIRAKICGLRASEAGQGCKDA-LQLLIEHSWERGERLDMQ 288

  Fly   306 GICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEEL----------QDLPEDIDEVSMF 360
            .:.......:|||::||:::....:..|.|:..|.::..|||          ||     :::.|.
Human   289 ALKQSSTELLFGGHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQD-----NKLDME 348

  Fly   361 QFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQ 425
            ...:|.::.|||||:|||.|..|...|..::...:||..:||...:...|.|....|..|....:
Human   349 ILEQLKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEE 413

  Fly   426 FLPERFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRN 474
            |.|:||:..:..:...|:|:||..|.|:|:|::|..:.:|:....:.|:
Human   414 FNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cyp4ac3NP_608918.1 p450 51..504 CDD:278495 86/374 (23%)
CYP26A1NP_000774.2 p450 14..492 CDD:299894 86/374 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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