Protein Alignment Cyp4ac3 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 402
• Identity: 103/402 - (25%)
• Similarity: 193/402 - (48%)
• Gaps: 39/402 - (9%)

  Fly   127 LGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKIL--DKNVGFELELNQIIPQ 189
            :...:.::.|::|...|..|:|.|....|:....:.::.....:|.|  :...|..:.:..::..
Mouse   114 MSKSISLAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQYGDILVKYLRQEAEKGKPVAVKDVLGA 178

  Fly   190 FTLNNICETALGVKLDDMSEGN----EYRKAIHDFEIVFNQRMCNPLMFFNWYF-FLFGDYKKYS 249
            ::::.|..|..||.:|.::...    |..|.:..|:..      :||......| ||...|:..:
Mouse   179 YSMDVIISTTFGVNIDSLNNPEDPFVENAKKVLRFDYF------DPLSLSVALFPFLTPIYEMLN 237

  Fly   250 RIL---RTIHGFSSGIIQRKRQQFKQKQLGQVDEFGKKQRYAMLDTLLAAEAEGKIDHQGICD-E 310
            ..:   .:|..|...:.:....:...||..:||..     |.|::..  .:::.|..|:.:.: |
Mouse   238 ICMFPKDSIEFFKKFVDRMTENRLDSKQKHRVDFI-----YLMMEAY--NKSKDKDSHKALSEIE 295

  Fly   311 VNT----FMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQD-----LPEDIDEVSMFQFNELI 366
            :..    |:|.||:|||:.|.||:..||.|.|:|::..||:.:     .|...|.|...::
Mouse   296 ITAQSIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAMEY---- 356

  Fly   367 HLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQFLPERF 431
             |:.|:.|:|||:|....:.|.|.::..:||:.:||.:.:.|..|.:..|.:|:|:|.:|.||||
Mouse   357 -LDMVLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERF 420

  Fly   432 LPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLE-DLTFENGIVLR 495
            ..||..:..|:.::||..|||||||.:|.::.:|:.|..|::||...|..:.: .|.....::|:
Mouse   421 SKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSRELLLQ 485

  Fly   496 TQQNIKVKFEAR 507
            ..:.|.:|...|
Mouse   486 PVKPIVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	101/395 (26%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	101/396 (26%)