Protein Alignment Cyp4ac3 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 524
• Identity: 137/524 - (26%)
• Similarity: 234/524 - (44%)
• Gaps: 91/524 - (17%)

  Fly     1 MWIALLGSSLLIGAL-WL----LLRQLNKTYFILSLCKRVRTADGSPLESKVFVVPGKTRFGNNL 60
            ||     .|:::..| |:    ||..:......|:.|..::.     :..|...:||..|   :.
 Frog     1 MW-----HSVIVHCLSWVYSGFLLIIIGAVVAFLAYCAYIKY-----MHLKYDDIPGPPR---DS 52

  Fly    61 DLLNLTPANIFSYIRESTAKANGQNYI--------WNFLFAPEYNI----------VRAEDAEEI 107
            .||...|         :.:||. :||.        |..::.|.:.|          ...|..:|.
 Frog    53 FLLGHIP---------TLSKAE-ENYSVVHDLFLHWAEIYGPVFKINILHRVMIYSTSPESVKEC 107

  Fly   108 FQSTKIT----TKNMSYELI-RPFLGDGLLISID-QKWHTRRKTLTPAFHFNILQSFLSIFKEES 166
            ..|:|..    |.|..:.|. :.|||.|||...| ..|:.:|:.:.|||....|:..:.||.|.:
 Frog   108 LMSSKYPKDPYTYNQLFNLFGKRFLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERA 172

  Fly   167 KKFI-KILDKNVGF-ELELNQIIPQFTLNNICETALGVKLDDMSEGN--EYRKAIHDFEIVFNQR 227
            ::.: |:.:|..|. |:.::.||.:.||:.|.:.|.|:.| .:.|||  ::..||........:.
 Frog   173 EQMMEKLEEKADGHQEVSMHSIINRVTLDVITKVAFGMDL-GLVEGNKTDFPNAISKVLTGMMRY 236

  Fly   228 MCNPLM-FFNWYFFLFGDYKKYSRILRTIHGFSSG---IIQRKRQQFKQKQLGQVDEFGKKQRYA 288
            |.||.| :|..::....:.::.:.:||     .:|   |.|||:.....::|         .:..
 Frog   237 MQNPYMQYFPKHWAFVREVQESADLLR-----KTGKECISQRKKAMQNGEEL---------PKDI 287

  Fly   289 MLDTLLAAEAEGKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLPED 353
            :...|..||.|..:|.:.:.|...||...|.:||:..|.||::.|....::..:...|:.::...
 Frog   288 LTKILQCAELENALDDEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGF 352

  Fly   354 IDEVSMFQFNELIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDAR 418
            ..::|......|.::..|:|||||.:|..|...|...|:::..|:.:|....|:.:.|.:.|..:
 Frog   353 KRDISYDDIQNLNYMTQVLKESLRFYPPGPGTSRYLKEDTIFEGIKIPGGVSITFNTYVMGRMEK 417

  Fly   419 HFPKPNQFLPERFLPENSVNRHP------FAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIR--NF 475
            .|..|.:|.||||        ||      |.:.||:.|||:|:||.|..||.||:|:.:|:  .|
 Frog   418 FFQDPCKFDPERF--------HPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEF 474

  Fly   476 KLLP 479
            :|:|
 Frog   475 ELVP 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	117/433 (27%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	117/430 (27%)