Protein Alignment Cyp4ac3 and Cyp3a59

DIOPT Version :10

• Sequence 1: NP_608918.1
• Gene: Cyp4ac3 / 33756
• FlyBaseID: FBgn0031695
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 471
• Identity: 125/471 - (26%)
• Similarity: 220/471 - (46%)
• Gaps: 53/471 - (11%)

  Fly    70 IFSY------IRESTAKANGQNYIWNFLFAPEYNIVRAEDAEEIFQSTKITTKNMSYELI--RP- 125
            ||:|      ..|...|..|:  ||.|...|: .|:...|.|.|    ||......|.:.  ||
Mouse    50 IFNYFDGMWKFDEDCYKKYGK--IWGFYVGPK-PILAIMDPEII----KIVLVKECYSVFTNRPT 107

  Fly   126 -----FLGDGLLISIDQKWHTRRKTLTPAFHFNILQSFLSIFKEESKKFIKIL--DKNVGFELEL 183
                 ||...:.||.|::|...|..|:|.|....|:....|.::.....::.|  ::..|..:.:
Mouse   108 LGPVGFLKKSITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQYGDILVRNLRREEEKGEPINM 172

  Fly   184 NQIIPQFTLNNICETALGVKLDDMSEGNEYRKAIHDFEIVFNQRMCNPLMFFNWYF-FLFGDYK- 246
            ..|...::::.|..|:.||.:|.::  |.....:...:.:...::.:|.:.....| ||...|:
Mouse   173 KDIFGAYSMDVITGTSFGVNIDSLN--NPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIYEM 235

  Fly   247 -KYSRILRTIHGFSSGIIQR-KRQQFKQKQLGQVD----------EFGKKQRYAMLDTLLAAEAE 299
             ..|...|....|....::| |:::...||..:||          ..|::.:.|:.|..:||:|.
Mouse   236 LNLSIFPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQAV 300

  Fly   300 GKIDHQGICDEVNTFMFGGYDTTSTSLIFTLLLLALHADVQERCYEELQDLPEDIDEVSMFQFNE 364
                         .|:|||||.||||:...:..||.|.|||::..:|:.....:...|:.....:
Mouse   301 -------------IFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMD 352

  Fly   365 LIHLECVIKESLRLFPSAPIIGRTCIEESVMNGLVLPKNAQISIHIYDIMRDARHFPKPNQFLPE 429
            :.:|:.|:.|||||:|:|..:.|...::..:||:.:||...:.|.||.:.|:..::|:|.:|.|.
Mouse   353 MEYLDMVVNESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPG 417

  Fly   430 RFLPENSVNRHPFAFVPFSAGPRNCIGQKFGVLEIKVLLAAVIRNFKLLPATQLE-DLTFENGIV 493
            ||..||..|..|:.::||..|||||:..:|.::.:|:.:..|::||.:.|..:.: .|......|
Mouse   418 RFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISREPV 482

  Fly   494 LRTQQNIKVKFEARVK 509
            .:.::.|.:|..:|.|
Mouse   483 FQPEKPIILKVVSRDK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac3	NP_608918.1	CYP4	87..502	CDD:410721	116/439 (26%)
Cyp3a59	NP_001098630.1	CYP3A	67..492	CDD:410743	117/446 (26%)