Protein Alignment Cyp4ac2 and ERG5

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_013728.1
• Gene: ERG5 / 855029
• SGDID: S000004617
• Length: 538
• Species: Saccharomyces cerevisiae
• Alignment Length: 403
• Identity: 92/403 - (22%)
• Similarity: 164/403 - (40%)
• Gaps: 74/403 - (18%)

  Fly   105 AEEILQSSKLI---TKNMIYELLKP----FLGEGLLISTDQKWHS-RRKALTPAFHFKVLQSFL- 160
            |.:||||||.:   ..::..::|:|    ||        |.|.|: .||:|...|..:.|..:|
Yeast   124 ARKILQSSKFVKPCVVDVAVKILRPCNWVFL--------DGKAHTDYRKSLNGLFTKQALAQYLP 180

  Fly   161 ---IIFKEECNKLVKVLHQSVNME-----LELNQVIPQFTLNNVCETALGVKLDDLSEGIRYRQS 217
               .|..:..:|.|: |.:..|.|     .|:.:::...:||:.|.
Yeast   181 SLEQIMDKYMDKFVR-LSKENNYEPQVFFHEMREILCALSLNSFCG------------------- 225

  Fly   218 IHAIEEVMQQRLCNPFF-----YNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSN-QL 276
             :.|.|...:::.:.::     ..:|.|.:...|.|.....|.| :.:..|.|....:.|.: ..
Yeast   226 -NYITEDQVRKIADDYYLVTAALELVNFPIIIPYTKTWYGKKTA-DMAMKIFENCAQMAKDHIAA 288

  Fly   277 GQE-----DEFGKKQRYAMLDTLLAAEADGQIDH-----QGICDEVNTFMFEGYDTTSTCLIFTL 331
            |.:     |.:.|    .|.|...:.:.|.:|.|     :.|.:.|.||:|...|.:|:...:..
Yeast   289 GGKPVCVMDAWCK----LMHDAKNSNDDDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLF 349

  Fly   332 LMLALHEDVQKKCYEEIKYL--PDDSDDISVFQFNELVYMECVIKESLRLFP---SVPFIGRRCV 391
            .::|...||..|..||...:  .|.|.::::....::.|...||||:||..|   .||::.::
Yeast   350 QIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPVLMVPYVVKK-- 412

  Fly   392 EEGVVNGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCI 456
            ...|......||...:...||..:.|...:.||..|.|:|:...:..:.....::.|..|...|:
Yeast   413 NFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWVEGSKASEAKKNWLVFGCGPHVCL 477

  Fly   457 GQKFAILEIKVLL 469
            ||.:.::....||
Yeast   478 GQTYVMITFAALL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	92/403 (23%)
ERG5	NP_013728.1	CYP61_CYP710	103..522	CDD:410703	92/403 (23%)