DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac2 and CYP715A1

DIOPT Version :9

Sequence 1:	NP_608917.3	Gene:	Cyp4ac2 / 33755	FlyBaseID:	FBgn0031694	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_200053.2	Gene:	CYP715A1 / 835316	AraportID:	AT5G52400	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	538	Identity:	125/538 - (23%)
Similarity:	229/538 - (42%)	Gaps:	117/538 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FAAPLVIFIFRKLWAHLNRTYFILSLCKR------------IRTEDGSLLESKIYVAPSKT-RFG 58
            |....|.:||.|:        |::.:|..            :|.:  ..|....:|.|:.: .||
plant     4 FEMSRVWYIFFKV--------FVVVICLMFLKLFLRCWIWPVRAQ--KKLRGNGFVGPAPSFPFG 58

  Fly    59 NNFDLV----------NFTSESIFNFMRDASA--------KAKGRNYLWYFFHAPMYNIVRAEEA 105
            |..|:.          |..|.:|.|....:.|        :..|:.::::....|...:...|..
plant    59 NLNDMKKLKMASVVVDNSKSSTIINHDIHSIALPHFARWQQEYGKVFVYWLGIEPFVYVADPEFL 123

  Fly   106 EEILQSSKLITK-----NMIYELLKPFLGEGLLISTDQKWHSRRKALTPAF---HFKVLQSFLII 162
            .  :.|..::.|     |:..:..:|..|.||::.....|...|..:||||   :.||:.:.::
plant   124 S--VMSKGVLGKSWGKPNVFKKDREPMFGTGLVMVEGDDWTRHRHIITPAFAPLNLKVMTNMMV- 185

  Fly   163 FKEECNKLVKVLHQSV-NM----ELELNQVIPQFTLNN---------VCETALGVKLDDLSEGIR 213
                         :|| ||    .:::|...|:|.:.:         :.:|:.||..::   |.:
plant   186 -------------ESVSNMLDRWGIQINSGNPEFDMESEIIGTAGEIIAKTSFGVTGEN---GTQ 234

  Fly   214 YRQSIHAIEEVM--QQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSS---NIIEKRR-SLFK 272
            ..:::.|::..:  ..|.....|.||:      .|::.|....:.||...   :.|.||: ||.:
plant   235 VLKNLRAVQFALFNSNRYVGVPFSNIL------SYKQTVKAKGLGHEIDGLLLSFINKRKISLAE 293

  Fly   273 SNQLGQEDEFGKKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALH 337
                      |..|.:.:|..||.|:..|....:.:.||..||.|.|::||:..|.:|.::||:|
plant   294 ----------GDDQGHDLLGMLLKADQKGNFTAKELVDECKTFFFAGHETTALALTWTFMLLAIH 348

  Fly   338 EDVQKKCYEEIKYLPDDSDDISVFQFNELV---YMECVIKESLRLFPSVPFIGRRCVEEGVVNGL 399
            .:.|....|||:.:..||.    .::|:|.   .|..|:.|.|||:|..|...|:...:..|||.
plant   349 PEWQDTIREEIREVIGDSK----IEYNKLAGLKKMSWVMNEVLRLYPPAPNAQRQARNDIEVNGR 409

  Fly   400 IMPKNTQINIHLYEIMRDARHFSNP-KMFQPDRFFPENTVN---RHPFAFVPFSAGQRNCIGQKF 460
            ::|..|.|.|.:..:..|...:.:. ..|:|:||  :..::   ::...::||..|.|.|||:..
plant   410 VIPNGTNIWIDVVAMHHDVELWGDDVNEFKPERF--DGNLHGGCKNKMGYMPFGFGGRMCIGRNL 472

  Fly   461 AILEIKVLLAAVIRNFKI 478
            ..:|.|::|:.|:..|:|
plant   473 TTMEYKIVLSLVLSRFEI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	114/475 (24%)
CYP715A1	NP_200053.2	p450	16..519	CDD:299894	120/526 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.970