DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac2 and CYP96A2

DIOPT Version :9

Sequence 1:	NP_608917.3	Gene:	Cyp4ac2 / 33755	FlyBaseID:	FBgn0031694	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_194944.1	Gene:	CYP96A2 / 829349	AraportID:	AT4G32170	Length:	506	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	123/550 - (22%)
Similarity:	211/550 - (38%)	Gaps:	123/550 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FIFRK-------LWAHLNRTYFILSLCKRIRTEDGSLLESKIYVAPSK-TRFGNNFDLVNFTSES 70
            |:|:|       .|..|.....:|....||......:||:.....|.| .||.....|:.....:
plant    22 FLFKKPHGRYPRNWPVLRMLPAMLKALHRIYDYSVKILETSDLTFPFKGPRFTGMDMLLTVDPAN 86

  Fly    71 IFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLIS 135
            |.:.|        ..|:         .|.::..|.:::..                .||:..:.:
plant    87 IHHIM--------SSNF---------SNYIKGPEFQDVFD----------------VLGDSFITT 118

  Fly   136 TDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNK--LVKVLHQ--SVNMELELNQVIPQFTLNNV 196
            ..:.|.:.||:.....|.:..|.|.:.......|  ||.:|:.  .....|:|..|..:||.:.:
plant   119 DSELWKNMRKSYQAMLHSQEFQRFSMSTMTSKLKYGLVPLLNHFAEEGTTLDLQSVFGRFTFDTI 183

  Fly   197 C----------------ETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGD 245
            .                |......|||:.|||.||.        .:.|    |.:.:..:..||.
plant   184 FILVTGSDPRSLSIEMPEDEFAKALDDVGEGILYRH--------FKPR----FLWKLQNWIGFGQ 236

  Fly   246 YRKQVNNLKIAHEFSSNIIEKRRSLFKSNQ----LGQEDEFGKKQRYAMLDT----LLAAEADGQ 302
            .:|............:..|..:|...|.:|    .|.:|..   ..:..|||    ||     ..
plant   237 EKKLTEANATFDRVCAKYISAKREEIKRSQGTSNGGSQDLL---TSFIKLDTTKYKLL-----NP 293

  Fly   303 IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDS-DDISVFQFNEL 366
            .|.:.:.|.:..|:..|.|||:|.|.:...:|:.:..|..|.::||....|.| ...|....::|
plant   294 SDDKFLRDNILAFILAGRDTTATALSWFFWLLSENPHVVAKIHQEININTDLSRTGNSQENVDKL 358

  Fly   367 VYMECVIKESLRLFPSVPFIGRRCVEEGVV-NGLIMPKNTQINIHLYEIMR-------DARHFSN 423
            ||:...:.|::||:|.|.|..:..::..|: :|..:..|::|.|.||.:.|       ||
plant   359 VYLHGALCEAMRLYPPVSFGRKSPIKSDVLPSGHKVDANSKIIICLYALGRMRAVWGEDA----- 418

  Fly   424 PKMFQPDRFFPENTVNRH--PFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNF--------KI 478
             ..|:|:|:..||...:|  .|.|:.|:||.|.|:|:..|:.::|::...::||:        ||
plant   419 -SQFKPERWISENGGIKHEPSFKFLSFNAGPRTCLGKHLAMTQMKIVAVEILRNYDIKVLQGQKI 482

  Fly   479 LPVTLLDDLTFENGIVLRTKQNIKVKLVHR 508
            :|..         |.:|..|..:::.:..|
plant   483 VPAL---------GFILSMKHGLQITVTKR 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	109/494 (22%)
CYP96A2	NP_194944.1	p450	1..503	CDD:416425	122/548 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8393
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010