DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4ac2 and CYP709B3

DIOPT Version :9

Sequence 1:	NP_608917.3	Gene:	Cyp4ac2 / 33755	FlyBaseID:	FBgn0031694	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_194501.1	Gene:	CYP709B3 / 828885	AraportID:	AT4G27710	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	137/521 - (26%)
Similarity:	225/521 - (43%)	Gaps:	89/521 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LFAAPLVIFIFRKLWAHLNRTYFI-----LSLCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVN 65
            |....|::|:..|:|    :..:|     |.|.||.:.:..|..:.||.       :||..::..
plant     9 LLTIVLLLFVVSKIW----KACWILLLRPLMLSKRFKKQGISGPKYKIL-------YGNLSEIKK 62

  Fly    66 FTSESIFNFMRDAS--------------AKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLIT 116
            ...|:....:...|              ....|..:|::....|...|...|.|:::|.|....|
plant    63 MKKEADLCVLDPNSNDIFPRVFPQYHQWMSQYGDTFLFWTGTKPTIYISNHELAKQVLSSKFGFT 127

  Fly   117 KNMIYELLKP----FLGEGLLISTDQKWHSRRKALTPAFHFKVLQSF--------LIIFKEECNK 169
               |..:.:|    ..|:||.......|...|:.|.|||....|::.        |.|| ||..|
plant   128 ---IIPVKRPEVFILFGKGLSFIQGDDWIRHRRILNPAFSMDRLKAMTQPMGDCTLRIF-EEWRK 188

  Fly   170 LVKVLHQSVNMELELNQVIPQFTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFF 234
            ..:  :..|.:::|:::...:.|.:.:..||.|   ...:|||...:|...:|:.....|.|.|.
plant   189 QRR--NGEVLIKIEISKEFHKLTADIIATTAFG---SSYAEGIELCRSQTELEKYYISSLTNVFI 248

  Fly   235 YNIVY------FFLFGDYRKQVNNLKIAHEFSSNIIEKR-RSLFKSNQLGQEDEFGKKQRYAMLD 292
            ....|      ..|:..::|..|::|       .||:.| :|..|:...| :|..|     .||.
plant   249 PGTQYLPTPTNLKLWELHKKVKNSIK-------RIIDSRLKSKCKTYGYG-DDLLG-----VMLT 300

  Fly   293 TLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEI------KYL 351
            ...:.|.:.::....|.:|...|.:.|..|||..|.:|.::|:||:..|:|..||:      ..:
plant   301 AAKSNEYERKMRMDEIIEECKNFYYAGQGTTSILLTWTTMLLSLHQGWQEKLREEVFNECGKDKI 365

  Fly   352 PDDSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMR 416
            ||..      .|::|..|..|:.|||||:..|..|.|...::..|..|.:||.|.|.|.|.::.|
plant   366 PDTD------TFSKLKLMNMVLMESLRLYGPVIKISREATQDMKVGHLEIPKGTSIIIPLLKMHR 424

  Fly   417 D-ARHFSNPKMFQPDRFFPENTVNR---HPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFK 477
            | |....:.:.|.|.||  ||.:::   ||.|.:|||.|.|.||.:.||::|.|.:|..:::.|:
plant   425 DKAIWGEDAEQFNPLRF--ENGISQATIHPNALLPFSIGPRACIAKNFAMVEAKTVLTMILQQFQ 487

  Fly   478 I 478
            :
plant   488 L 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	124/465 (27%)
CYP709B3	NP_194501.1	p450	9..517	CDD:299894	137/521 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050