Protein Alignment Cyp4ac2 and cyp46a1.5

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001417768.2
• Gene: cyp46a1.5 / 641477
• ZFINID: ZDB-GENE-051120-33
• Length: 501
• Species: Danio rerio
• Alignment Length: 543
• Identity: 129/543 - (23%)
• Similarity: 237/543 - (43%)
• Gaps: 105/543 - (19%)

  Fly     6 LFAAPLVIFIFRKLWA-HLNRTY----------FIL----SLCKRIRTEDGSLLESKIYVAPSKT 55
            |.||....|....|:. |:::.|          |:|    ||.|.:.::| ||:
Zfish    13 LLAAVFTAFFAYCLYVHHIHQKYDHIPGPPRDNFLLGHSPSLTKALYSDD-SLI----------- 65

  Fly    56 RFGNNFDLVNFTSESIFNFMRDASAKAKGRNYLWYFFHAPMYNI---------VRAEEAEEILQS 111
                 :||          |::            |...:.|:|.|         |...||.:.:..
Zfish    66 -----YDL----------FLQ------------WAEKYGPVYRINTLHYVTIVVYCPEATKTIMM 103

  Fly   112 SKLITKN-----MIYELL-KPFLGEGLLISTDQK-WHSRRKALTPAFHFKVLQSFLIIFKEECNK 169
            |...||:     .::.|. |.|||.||:.:.|.. |:.:|:.:.|||....|:|.:..|.|...:
Zfish   104 SPKYTKDPFVYRRVFNLFGKRFLGYGLITAVDHDIWYRQRRIMDPAFSSSYLRSLISTFDEMSER 168

  Fly   170 LVKVLHQSVNMELE--LNQVIPQFTLNNVCETALGVKLDDLSE-GIRYRQSIHAIEEVMQQRLCN 231
            |:..|.:..|.:..  ::.::...||:.:|:.|.||.|:.|:: ...::.::....:.|...:.:
Zfish   169 LMDKLEEIANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLTQKDSPFQNAVELCLKGMTFDVRD 233

  Fly   232 PFFYNIVYFFLFGDYRKQVNNLKIAHEF----SSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLD 292
            |.|..|...:      |.:..::.|.|.    ....|:.|::..|:.:...:|         :|.
Zfish   234 PLFRIIPKNW------KLIQQVREATELLRKTGEKWIQNRKTAVKNGEDVPKD---------ILT 283

  Fly   293 TLLAAEADGQI----DHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPD 353
            .:|.:..:..:    |.:.:.|...||...|.:||:..|.|.::.|..:.::.|:...|:..:..
Zfish   284 QILKSAEEQNVTSTEDFEQMLDNFVTFFMAGQETTANQLSFAIMELGRNPEIYKRAKAEVDEVLG 348

  Fly   354 DSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDA 418
            ...:||.....:|.|:..|:||:|||:|:.|...|...|:.|:||:.:|....:..:.:...|..
Zfish   349 TKREISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDMVINGIKIPGGCSVMFNSFVSQRLE 413

  Fly   419 RHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFK--ILPV 481
            :.|.:|..|.|.| |.||....: :.:.||:.|.|.||||.|:.:|.||:||.:::.|:  ::|.
Zfish   414 KFFKDPLKFDPKR-FDENAPKPY-YTYYPFALGPRTCIGQVFSQMEAKVVLAKLLQRFEFSLVPG 476

  Fly   482 TLLD-----DLTFENGIVLRTKQ 499
            ...|     .|..::|::...||
Zfish   477 QSFDIKDTGTLRPKSGVICYIKQ 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	111/450 (25%)
cyp46a1.5	NP_001417768.2	None