Protein Alignment Cyp4ac2 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 500
• Identity: 152/500 - (30%)
• Similarity: 255/500 - (51%)
• Gaps: 47/500 - (9%)

  Fly    26 TYFILSLCKRIRTEDGSLLESKIYVAPSKTR-FGNNFDLVNFTSESIFNFMRDASAKAKGRNYLW 89
            ||.....|:|:          :.:..|.|.. |..:..||..|.|.:....:..:...:|.. ||
Human    38 TYTFYDNCRRL----------QCFPQPPKQNWFWGHQGLVTPTEEGMKTLTQLVTTYPQGFK-LW 91

  Fly    90 YFFHAPMYNIVRAEEAEEILQSSKLIT-KNMI-YELLKPFLGEGLLISTDQKWHSRRKALTPAFH 152
            .....|:..:...:....|..:|..:. |:|| |..|||:||:|||:|...||...|:.||||||
Human    92 LGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFH 156

  Fly   153 FKVLQSFLIIFKEECNKLVKVLH---QSVNME----LELNQVIPQFTLNNVCETALGVKLDDLSE 210
            |.:|:.::.||    ||.|.::|   |.:..|    |::.:.|...||:::.:.....:.:...:
Human   157 FNILKPYMKIF----NKSVNIMHDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEK 217

  Fly   211 GIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQ 275
            ...|..:|..:...:::|......:....::|..|.::......:.|:|:..:|::||....:.
Human   218 PSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQ- 281

  Fly   276 LGQEDEFGKKQRYAMLD----TLLAAEADG-QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLA 335
             |.:|....|.:...||    .||:.:.|| ::..:.|..|.:||||||:|||::.|.:.|..||
Human   282 -GIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLA 345

  Fly   336 LHEDVQKKCYEEIKYLPDDSDDISVFQFNELV---YMECVIKESLRLFPSVPFIGRRCVEEGVV- 396
            .|.:.|::|.:|::.|..|.:.|.: ::::|.   ::...|||||||.|.||.|.|.|.::.|:
Human   346 KHPEYQEQCRQEVQELLKDREPIEI-EWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLP 409

  Fly   397 NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFA 461
            :|.::||.....|::..|..:...:.:|:::.|.||..||...|.|.||:|||||.||||||.||
Human   410 DGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFA 474

  Fly   462 ILEIKVLLAAVIRNFKILPV--------TLLDDLTFENGIVLRTK 498
            :.|:||:||..:.:|:|||.        .|:  |..|.|:.||.:
Human   475 MAEMKVVLALTLLHFRILPTHTEPRRKPELI--LRAEGGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	141/440 (32%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	139/450 (31%)