Protein Alignment Cyp4ac2 and CYP4F3

DIOPT Version :9

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_000887.2
• Gene: CYP4F3 / 4051
• HGNCID: 2646
• Length: 520
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 146/503 - (29%)
• Similarity: 247/503 - (49%)
• Gaps: 55/503 - (10%)

  Fly     8 AAP-LVIFIFRKLWAHLNR----TYFILSLCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVNFT 67
            |:| |::.:....|. |.|    ||.....|.|:|.         ....|.:..|..:..|::.:
Human    16 ASPWLLLLLVGASWL-LARILAWTYTFYDNCCRLRC---------FPQPPKRNWFLGHLGLIHSS 70

  Fly    68 SESIFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEI----LQSSKLITKNMI-YELLKPF 127
            .|.:  ....:.|...|....|:.  .|.:.|||......|    ...:.::.|:.: |..|||:
Human    71 EEGL--LYTQSLACTFGDMCCWWV--GPWHAIVRIFHPTYIKPVLFAPAAIVPKDKVFYSFLKPW 131

  Fly   128 LGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNM-------ELELN 185
            ||:|||:|..:||...|:.|||||||.:|:.::.||.|..|    ::|....:       .|::.
Human   132 LGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVN----IMHAKWQLLASEGSARLDMF 192

  Fly   186 QVIPQFTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQV 250
            :.|...||:::.:...........:...|..:|..:..::.:|......|....::|..|.::..
Human   193 EHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFR 257

  Fly   251 NNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLD----TLLAAEADG-QIDHQGICD 310
            ...::.|:|:..:|::||....|.  |.:|....|.:...||    .||:.:.|| ::..:.|..
Human   258 RACRLVHDFTDAVIQERRRTLPSQ--GVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRA 320

  Fly   311 EVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDS-------DDISVFQFNELVY 368
            |.:||||||:|||::.|.:.|..||.|.:.|::|.:|::.|..|.       ||::     :|.:
Human   321 EADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLA-----QLPF 380

  Fly   369 MECVIKESLRLFPSVPFIGRRCVEEGVV-NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRF 432
            :...|||||||.|.||.:.|.|.::.|: :|.::||.....|.::....:...:.:|:::.|.||
Human   381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF 445

  Fly   433 FPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILP 480
            .|:|...|.|.||:|||||.||||||.||:.|:||:|...:..|::||
Human   446 DPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	134/449 (30%)
CYP4F3	NP_000887.2	p450	52..515	CDD:365848	135/457 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154872
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850