Protein Alignment Cyp4ac2 and CYP26C1

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_899230.2
• Gene: CYP26C1 / 340665
• HGNCID: 20577
• Length: 522
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 90/419 - (21%)
• Similarity: 152/419 - (36%)
• Gaps: 71/419 - (16%)

  Fly    95 PMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLISTDQKWH-SRRKALTPAFHFKVLQS 158
            |:..:..||....||.....:.::...:.....||...|:....:.| .|||.|...|....|:.
Human    92 PVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALER 156

  Fly   159 FLIIFKEECNKLVKVLHQSVNM------ELELNQVIPQFTLNNVCETALGVKLDDLSEGIRYRQS 217
            ::       .:|...|...|..      .:.:.......|........||::||:.......|..
Human   157 YV-------PRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTF 214

  Fly   218 IHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEF 282
            ...:|.:....|..|          |...||.:......|......|.::....|:.:.|.
Human   215 EQLVENLFSLPLDVP----------FSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGD---- 265

  Fly   283 GKKQRYAMLDTLL--AAEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCY 345
                   .||.::  |.|...:...|.:.:.....:|..:.||::.....:|:|..|.....|..
Human   266 -------ALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIR 323

  Fly   346 EEI-------------------KYLPDD---SDDISVFQFNELVYMECVIKESLRLFPSVPFIGR 388
            ||:                   :..|.|   ..|:|:.....|.|::||:||.|||.|.|....|
Human   324 EELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYR 388

  Fly   389 RCVEEGVVNGLIMPKNTQINIHLYEIMRD-----ARHFSNPKMFQPDRFFPENTVNR---HPFAF 445
            ..:....::|..:||...:   :|.| ||     |.:.|.|:.|.|:||......:|   ..|.:
Human   389 TALRTFELDGYQIPKGWSV---MYSI-RDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHY 449

  Fly   446 VPFSAGQRNCIGQKFAILEIKVLLAAVIR 474
            :||..|.|:|:||:.|...:::|...::|
Human   450 IPFGGGARSCLGQELAQAVLQLLAVELVR 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	90/419 (21%)
CYP26C1	NP_899230.2	CYP26C1	59..508	CDD:410729	90/419 (21%)