Protein Alignment Cyp4ac2 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_997831.1
• Gene: cyp26b1 / 324188
• ZFINID: ZDB-GENE-030131-2908
• Length: 511
• Species: Danio rerio
• Alignment Length: 483
• Identity: 117/483 - (24%)
• Similarity: 196/483 - (40%)
• Gaps: 94/483 - (19%)

  Fly    76 RDASAKAK-----------GRNYLWYF----FHA-----------------PMYNIVRAEEAEEI 108
            ||.|.|..           |....|:|    |||                 |:..:..||...::
Zfish    41 RDKSCKLPMPKGSMGFPIIGETCHWFFQGAGFHASRRQKYGNVFKTHLLGRPLIRVTGAENVRKV 105

  Fly   109 LQSS-KLITKNMIYELLKPFLGEGLLISTDQKWH-SRRKALTPAFHFKVLQSFLIIFKEECNKLV 171
            |... .|:|.:. .:.....||...|.::....| .|||.....|..:.|:|:|...::...:.:
Zfish   106 LMGEHSLVTVDW-PQSTSTLLGPNSLANSIGDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETL 169

  Fly   172 KVLHQS---VNMELELNQVIPQFTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPF 233
            :|...:   :|:..|..::    :.|......||.::.:        :.:|.:....|:.:.|.|
Zfish   170 RVWSSNPDPINVYRESQRL----SFNMAVRVLLGFRIPE--------EEMHCLFSTFQEFVENVF 222

  Fly   234 FYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLL--A 296
              ::.....|..|||.:.    |.:.....|||   ..:...|..:   ||....| ||.||  |
Zfish   223 --SLPIDLPFSGYRKGIR----ARDSLQKSIEK---AIREKPLHTQ---GKDYTDA-LDVLLESA 274

  Fly   297 AEADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIK---YLPDD---S 355
            .|.:.::..|.:.:.....:|..:.||::.....::.|..|..|.:|..||::   .|.|.   .
Zfish   275 KENNTELTMQELKESTIELIFAAFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDGCLCQ 339

  Fly   356 DDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARH 420
            .::.:.....|.|::|||||.||||..|....|...:...::|:.:||...:   :|.| ||...
Zfish   340 GELRLDSIISLKYLDCVIKEVLRLFAPVSGGYRIATQTFELDGVQVPKGWSV---MYSI-RDTHD 400

  Fly   421 ----FSNPKMFQPDRFFPENTVNRH-PFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILP 480
                |.:.:.|.||||.||.:.:|. .|.::||..|.|:|:|::.|.|.:           |:|.
Zfish   401 TSAVFKDVEAFDPDRFSPERSEDREGRFHYLPFGGGVRSCLGKQLATLFL-----------KLLA 454

  Fly   481 VTLLDDLTFENGIVLRT-KQNIKVKLVH 507
            |.|.....||  :..|| .:.|.|.:||
Zfish   455 VELAGGSRFE--LSTRTFPRMISVPVVH 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	110/458 (24%)
cyp26b1	NP_997831.1	cytochrome_P450	60..489	CDD:477761	113/464 (24%)