Protein Alignment Cyp4ac2 and Cyp4a3

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 147/535 - (27%)
• Similarity: 254/535 - (47%)
• Gaps: 80/535 - (14%)

  Fly     2 FLEVLFAAPLVIFIFRKLWAHLNRTYFILSLCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVNF 66
            |.:..|...|.:.:|:.:..:|.|.:.:.:|             .|....||...:|:  ||.:.
  Rat    18 FFQGAFLLSLFLVLFKAVQFYLRRQWLLKAL-------------EKFPSTPSHWLWGH--DLKDR 67

  Fly    67 TSESIFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFL--- 128
            ..:.:..::.    |..|....|.........:...:..:.:|..|...... ||:.|.|::
  Rat    68 EFQQVLTWVE----KFPGACLQWLSGSKTRVLLYDPDYVKVVLGRSDPKASG-IYQFLAPWIVSG 127

  Fly   129 -GEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNM------------ 180
             |.|||:...:||....:.||||||:.:|:.:           ||::..||::
  Rat   128 TGYGLLLLNGKKWFQHWRMLTPAFHYGILKPY-----------VKIMADSVSIMLDKWEKLDDQD 181

  Fly   181 -ELELNQVIPQFTLNNVCETAL----GVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYF 240
             .||:...:...||:.|.:.|.    .|:||..|..  |.:::..:..:...|:.:.|:.|.:.:
  Rat   182 HPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRS--YTKAVEDLNNLTFFRVRSAFYGNSIIY 244

  Fly   241 FLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEF---GKKQRYAMLDTLLAAE-ADG 301
            .:..|.|......:||||.:..:|:.|::     ||..|:|.   .||:....||.||.|: .||
  Rat   245 NMSSDGRLSRRACQIAHEHTDGVIKMRKA-----QLQNEEELQKARKKRHLDFLDILLFAKMEDG 304

  Fly   302 Q-IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNE 365
            : :..:.:..||:||||||:|||::.:.:....||.|.:.|::|.||::.:..|...::....::
  Rat   305 KSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQ 369

  Fly   366 LVYMECVIKESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQ 428
            :.|....|||:|||:|.||.:.|. :...|.  :|..:||.....|.:|.:..:..::.|||:|.
  Rat   370 ISYTTMCIKEALRLYPPVPSVSRE-LSSPVTFPDGRSIPKGITTTILIYGLHHNPSYWPNPKVFD 433

  Fly   429 PDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILP---------VTLL 484
            |.||.|::.  ||..|::|||.|.|||||::||:.|:||.:|..:..|::||         ..|:
  Rat   434 PSRFSPDSP--RHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMARLV 496

  Fly   485 DDLTFENGIVLRTKQ 499
              |..:|||.||.|:
  Rat   497 --LKSKNGIHLRLKK 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	133/453 (29%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	131/464 (28%)