Protein Alignment Cyp4ac2 and CYP4V2

DIOPT Version :9

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_997235.3
• Gene: CYP4V2 / 285440
• HGNCID: 23198
• Length: 525
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 173/426 - (40%)
• Similarity: 259/426 - (60%)
• Gaps: 15/426 - (3%)

  Fly    95 PMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSF 159
            ||..:..||..|.||.|||.|.|:.:|:.|:|:||.|||.||..||.||||.|||.|||.:|:.|
Human    98 PMVALYNAENVEVILTSSKQIDKSSMYKFLEPWLGLGLLTSTGNKWRSRRKMLTPTFHFTILEDF 162

  Fly   160 LIIFKEECNKLVKVLHQSVNME-LELNQVIPQFTLNNVCETALGVKL----DDLSEGIRYRQSIH 219
            |.|..|:.|.|||.|.:.:|.| ......|....|:.:||||:|..:    :|.||   |.::::
Human   163 LDIMNEQANILVKKLEKHINQEAFNCFFYITLCALDIICETAMGKNIGAQSNDDSE---YVRAVY 224

  Fly   220 AIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFG- 283
            .:.|::.:|:..|:.:..:::.:|.:..:...:|:|.|.|::::|.:|.:...:|:..:.|..|
Human   225 RMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLQILHTFTNSVIAERANEMNANEDCRGDGRGS 289

  Fly   284 ---KKQRYAMLDTLLAAEAD--GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKK 343
               |.:|.|.||.||:...|  .::.|:.|.:||:||||||:|||:..:.::|.:|..:.:||||
Human   290 APSKNKRRAFLDLLLSVTDDEGNRLSHEDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKK 354

  Fly   344 CYEEIKYLPDDSD-DISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQI 407
            ...|:..:...|| ..:|....:|.|:||||||:||||||||...|...|:..|.|..:.|.|:.
Human   355 VDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEA 419

  Fly   408 NIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAV 472
            .|..|.:.||.|:|.||:.|||:||||||...|||:|:||||||.|||||||||::|.|.:|:.:
Human   420 VIIPYALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCI 484

  Fly   473 IRNFKILPVTLLDDLTFENGIVLRTKQNIKVKLVHR 508
            :|:|.|......::|..|..::||....|.:||..|
Human   485 LRHFWIESNQKREELGLEGQLILRPSNGIWIKLKRR 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	170/421 (40%)
CYP4V2	NP_997235.3	p450	55..517	CDD:278495	170/421 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154659
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.950