Protein Alignment Cyp4ac2 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 122/459 - (26%)
• Similarity: 215/459 - (46%)
• Gaps: 70/459 - (15%)

  Fly    88 LWYFF--HAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPF-----------LGEGLLISTDQK 139
            :|..|  ..|::.|...|..:.:|          :.|....|           :|:.:.:|.|::
  Rat    71 IWGLFDGQMPLFAITDTEMIKNVL----------VKECFSVFTNRRDFGPVGIMGKAISVSKDEE 125

  Fly   140 WHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNMELELNQVIPQFTLNNVCETALGVK 204
            |...|..|:|.|....|:....:.::..:.|||.|.|.....:.:.:|...::::.:..|:.||.
  Rat   126 WKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEKGKPVPVKEVFGAYSMDVITSTSFGVN 190

  Fly   205 LDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYF-FLFGDY----------------RKQVNN 252
            :|.|:.  .....:...:::::....:|.|.::|.| ||...|                :|.|..
  Rat   191 VDSLNN--PKDPFVEKAKKLLRIDFFDPLFLSVVLFPFLTPVYEMLNICMFPKDSIEFFKKFVYR 253

  Fly   253 LKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMF 317
            :|   |...:.::|.|..|....:...::...|:.:..|       :|.:|..|.|     .|:|
  Rat   254 MK---ETRLDSVQKHRVDFLQLMMNAHNDSKDKESHTAL-------SDMEITAQSI-----IFIF 303

  Fly   318 EGYDTTSTCLIFTLLMLALHEDVQKKCYEEI-KYLPDDS----DDISVFQFNELVYMECVIKESL 377
            .||:.||:.|.|.|..||.|.|.|||..||| :.||:.:    |.:.     |:.|::.|:.|:|
  Rat   304 AGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVM-----EMEYLDMVLNETL 363

  Fly   378 RLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHP 442
            ||:|....:.|.|.::..:||:.|||.:.:.|..|.:.||.:|:..|:.|:|:||..||..:..|
  Rat   364 RLYPIGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHWPEPEEFRPERFSKENKGSIDP 428

  Fly   443 FAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPV--TLLDDLTFENGIVLRTKQNIKVKL 505
            :.::||..|.|||||.:||::.:|:.|..|::||...|.  |.:.......|::..||. |.:|:
  Rat   429 YVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQIPLKLSRQGLLQPTKP-IILKV 492

  Fly   506 VHRE 509
            |.|:
  Rat   493 VPRD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	119/451 (26%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	119/452 (26%)