Protein Alignment Cyp4ac2 and Cyp4a29

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001093653.1
• Gene: Cyp4a29 / 230639
• MGIID: 3717143
• Length: 509
• Species: Mus musculus
• Alignment Length: 514
• Identity: 134/514 - (26%)
• Similarity: 249/514 - (48%)
• Gaps: 36/514 - (7%)

  Fly     2 FLEVLFAAPLVIFIFRKLWAHLNRTYFILSLCKRIRTEDGSLLESKIYVAPSKTRFGNNFDLVNF 66
            ||:|:|...|::.:|:....:|.|.:.:.:|             .:....||...||:   .:.|
Mouse    18 FLQVIFLIGLLLLLFKAAQHYLRRQWLLRAL-------------YQFPSPPSHWLFGH---CLQF 66

  Fly    67 TSESIFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLITKNMIYELLKPFLGEG 131
            ..:....::.....|..|....|.:.......:...:..:.||  .:...|..:|..|.|:||.|
Mouse    67 KVDEELRWILRYLEKFPGAFLHWIWGSHVFIKVCDPDYMKVIL--GRADPKASLYRFLTPWLGHG 129

  Fly   132 LLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSV--NMELELNQVIPQFTLN 194
            |......:|...|:.||||||:.:|:.::.|..:....:::...|..  ::.||:...|....|:
Mouse   130 LFFLNGDEWFQHRRLLTPAFHYDILKPYVGIMADSVQVMLEKWEQIACQDITLEIFHPISLMMLD 194

  Fly   195 NVCETAL----GVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYFFLFGDYRKQVNNLKI 255
            .:.:.|.    .|:||..|:.  |.|::..:..::..|:.|.|.:|.:.:.|....|:..:..:|
Mouse   195 TIMKYAFSYQGSVQLDRSSQA--YLQAVSDLNNLVTSRMKNVFLHNDIIYNLTSHSRRTNSACQI 257

  Fly   256 AHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEAD--GQIDHQGICDEVNTFMFE 318
            |||.:..:::.|::..:.|:  ...:...|:....||.||.:..|  ..:..:.:..||::.||.
Mouse   258 AHEHTDRVVKLRKAQLQDNK--SMKKLRGKRCLDFLDILLLSRMDDGSSLSDKALRAEVDSLMFG 320

  Fly   319 GYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNELVYMECVIKESLRLFPSV 383
            |:||.::.:.:....||.|.|.|::|.||::.|..|...|:....:::.|....|||:|||:|.:
Mouse   321 GHDTPASGISWVFYALATHPDHQQRCREEVQSLLGDGSPITWDHLHQMPYTTMCIKEALRLYPPI 385

  Fly   384 PFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFV 446
            |.:||: :...|.  :|..:||...:.:|.|.:..:.:.:.||::|.|.| |..|:| :|..||:
Mouse   386 PSVGRK-LSTPVTFPDGRSLPKGITVLLHFYALHHNPKVWPNPEVFDPSR-FAMNSV-QHSHAFL 447

  Fly   447 PFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFENGIVLRTKQNIKVKL 505
            |||.|.|||||:..|:..:||.:|..:..|::||......:..:. :||::|..|.:.|
Mouse   448 PFSGGSRNCIGKHLAMNVLKVAVALTLLRFELLPDPSRVPIPTQQ-LVLKSKNGIYLHL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	118/428 (28%)
Cyp4a29	NP_001093653.1	CYP4B-like	75..504	CDD:410771	119/438 (27%)