Protein Alignment Cyp4ac2 and CYP4Z1

DIOPT Version :9

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_835235.1
• Gene: CYP4Z1 / 199974
• HGNCID: 20583
• Length: 505
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 123/468 - (26%)
• Similarity: 233/468 - (49%)
• Gaps: 74/468 - (15%)

  Fly    89 WYFFHAPMYNIVRAEEAEEILQS-----------------------SKLITKN------MIYELL 124
            |::.|...|.:...|...::::.                       :|::.|.      :.:::|
Human    53 WFYGHKEFYPVKEFEVYHKLMEKYPCAVPLWVGPFTMFFSVHDPDYAKILLKRQDPKSAVSHKIL 117

  Fly   125 KPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVL--HQSVNMELELNQV 187
            :.::|.||:.....||...|:.:.|.|:..:|:.|:.:..|....::...  |.:.|..|||.|.
Human   118 ESWVGRGLVTLDGSKWKKHRQIVKPGFNISILKIFITMMSESVRMMLNKWEEHIAQNSRLELFQH 182

  Fly   188 IPQFTLNNVCETAL----GVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYN-IVYFF-----L 242
            :...||:::.:.|.    .::||...:.  |.:::..:.::..||:.|...:| :|:.|     :
Human   183 VSLMTLDSIMKCAFSHQGSIQLDSTLDS--YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQI 245

  Fly   243 FGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEADGQID--H 305
            |..:.:::      |:|:..:|:.|:...| ::|.|:..  :|:|:..||.||:|:::...|  .
Human   246 FSKFNQEL------HQFTEKVIQDRKESLK-DKLKQDTT--QKRRWDFLDILLSAKSENTKDFSE 301

  Fly   306 QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNELVYME 370
            ..:..||.||||.|:||||:.:.:.|..||.:.:.|::|.:||:.|..|...|:....:::.|..
Human   302 ADLQAEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTT 366

  Fly   371 CVIKESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFF 433
            ..|||.|||:..|..|. |.:::.:.  :|..:|....:.|:::.:..:...:.:|::|.|.||.
Human   367 MCIKECLRLYAPVVNIS-RLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFS 430

  Fly   434 PENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFENG------ 492
            .||:...||:||:|||||.||||||.|||:|.||.:|..:..||:.|         ::.
Human   431 RENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAP---------DHSRPPQPV 486

  Fly   493 --IVLRTKQNIKV 503
              :||::|..|.|
Human   487 RQVVLKSKNGIHV 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	123/468 (26%)
CYP4Z1	NP_835235.1	p450	47..500	CDD:278495	123/468 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154836
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840