Protein Alignment Cyp4ac2 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 478
• Identity: 109/478 - (22%)
• Similarity: 188/478 - (39%)
• Gaps: 113/478 - (23%)

  Fly    89 WYFFHAPMYNIVRAEEAEEILQSSKLITK-------NMIYELLKPFLGE-------GLLISTDQK 139
            |...:..:|.|........::....|:.:       |.....|.|..|:       .|..|...:
 Worm    60 WTKQYGKVYGITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKLNPIQGDPNKDKRVNLFSSQGHR 124

  Fly   140 WHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVL-----HQSVNMELELNQVIPQFTLNNVCET 199
            |...|...:|.|....|:. |....|||  .|::|     |......::|.....:|||:.:...
 Worm   125 WKRLRTISSPTFSNNSLRK-LKTTVEEC--AVELLRHIEQHTDGGQPIDLLDFYQEFTLDVIGRI 186

  Fly   200 ALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYF-FLFGDYRKQV------------- 250
            |:|                    :...|...||.   :.|. .:||:.||.:
 Worm   187 AMG--------------------QTDSQMFKNPL---LPYVRAVFGEPRKGLFLSGSLAPWIGPI 228

  Fly   251 ---------NNLK------IAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAAEAD 300
                     |.:|      |.|  :||.:|:|..|..:::....|. |:.|.:  :|..|.|::|
 Worm   229 LRMVMFSLPNIVKNPAVHVIRH--TSNAVEQRVKLRMADEKAGIDP-GEPQDF--IDLFLDAKSD 288

  Fly   301 G------------------QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEE 347
            .                  |:..:.|..:...|:..|:|||:..|.::..:||.|..||||..||
 Worm   289 DVELENNEDFTKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEE 353

  Fly   348 IKYLPDDSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGV-VNGLIMPKNTQINIHL 411
            |.....| .:::..|.::|.||||||||:||::|.......||..... :....:.:.|.|....
 Worm   354 IDRECAD-PEVTFDQLSKLKYMECVIKETLRMYPLGALANSRCCMRATKIGNYEIDEGTNILCDT 417

  Fly   412 YEIMRDARHF-SNPKMFQPDRFFPENTVNRHPF---AFVPFSAGQRNCIGQKFAILEIKVLLAAV 472
            :.:..|...: .:.:.|:|:|:   .:.:.|.:   .::||..|.|.|||.:.|.:|.|:||:.:
 Worm   418 WTLHSDKSIWGEDAEEFKPERW---ESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHI 479

  Fly   473 IRNFKI-------LPVTLLDDLT 488
            :|.:.:       :|:.|:...|
 Worm   480 LRKYTLEVCNKTQIPLKLIGSRT 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	109/478 (23%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	108/475 (23%)