Protein Alignment Cyp4ac2 and Cyp4a14

DIOPT Version :9

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 547
• Identity: 151/547 - (27%)
• Similarity: 255/547 - (46%)
• Gaps: 104/547 - (19%)

  Fly     2 FLEVLFAAPLVIFIFRKLWAHLNRTYFILSL----CKRI------RTEDGSLLESKIYVA--PS- 53
            |.:..|...|.:.:|:.:..:|.|.:.:.:|    |...      ..:|..|.:..|:|.  ||
Mouse    18 FFQWAFLLSLFLVLFKAVQFYLRRQWLLKTLQHFPCMPSHWLWGHHLKDKELQQILIWVEKFPSA 82

  Fly    54 --KTRFGNNFDLVNFTSESIFNFMRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEILQSSKLIT 116
              :...|:|..::.:..:.:...:..:..||.|
Mouse    83 CLQCLSGSNIRVLLYDPDYVKVVLGRSDPKASG-------------------------------- 115

  Fly   117 KNMIYELLKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNM- 180
               ||:...|::|.|||:...:||...|:.||||||:.:|:.:           ||::..|||:
Mouse   116 ---IYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPY-----------VKIMADSVNIM 166

  Fly   181 ------------ELELNQVIPQFTLNNVCETAL----GVKLDDLSEGIRYRQSIHAIEEVMQQRL 229
                        .||:...:...||:.|.:.|.    .|:||:.|:  .|.:::..:..:...||
Mouse   167 LDKWEKLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSK--LYTKAVEDLNNLTFFRL 229

  Fly   230 CNPFF-YNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEF---GKKQRYAM 290
            .|.|: |||:| .:..|.|...:..:||||.:..:|:.|:|     ||..|:|.   .||:....
Mouse   230 RNAFYKYNIIY-NMSSDGRLSHHACQIAHEHTDGVIKMRKS-----QLQNEEELQKARKKRHLDF 288

  Fly   291 LDTLLAAEADGQIDHQGICD-----EVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKY 350
            ||.||.|..:   |...:.|     ||:||||||:|||::.:.:....||.|.:.|::|.||::.
Mouse   289 LDILLFARME---DRNSLSDEDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEVQS 350

  Fly   351 LPDDSDDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYE 413
            :..|...::.....::.|....|||:|||:|.|..:.|. :...|.  :|..:||.....|.:|.
Mouse   351 ILGDGTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRE-LSSPVTFPDGRSIPKGITATISIYG 414

  Fly   414 IMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKI 478
            :..:.|.:.|||:|.|.||.|::  :.|..|::|||.|.|||||::||:.|:||.:|..:..|::
Mouse   415 LHHNPRFWPNPKVFDPSRFAPDS--SHHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLLRFEL 477

  Fly   479 LPVTLLDDLTFENGIVLRTKQNIKVKL 505
            ||......:.... :||::|..|.:.|
Mouse   478 LPDPTRIPVPIAR-LVLKSKNGIHLCL 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	p450	57..505	CDD:278495	136/475 (29%)
Cyp4a14	NP_031848.1	p450	52..501	CDD:278495	143/509 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850