Protein Alignment Cyp4ac2 and Cyp3a11

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 403
• Identity: 110/403 - (27%)
• Similarity: 210/403 - (52%)
• Gaps: 39/403 - (9%)

  Fly   128 LGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSV--NMELELNQVIPQ 190
            :.:.:.||.|.:|...|..|:|.|....|:....:.::..:.|||.|.|..  ...:.:..|:..
Mouse   114 MSKAISISKDDEWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGKPVTMKDVLGA 178

  Fly   191 FTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFFYNIVYF-FLFGDYRKQVNNL- 253
            ::::.:..|:.||.:|.|:.  .....:...:::::....:|..:::|.| ||...|  ::.|:
Mouse   179 YSMDVITSTSFGVNVDSLNN--PEDPFVEKAKKLLRFDFFDPLLFSVVLFPFLTPVY--EMLNIC 239

  Fly   254 ---KIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAA--EADGQIDHQGICD-EV 312
               |.:.||....:::    .|.::|..:    :|.|...|..::.:  .:..::.|:.:.| |:
Mouse   240 MFPKDSIEFFKKFVDR----MKESRLDSK----QKHRVDFLQLMMNSHNNSKDKVSHKALSDMEI 296

  Fly   313 NT----FMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEI-KYLPDDS----DDISVFQFNELVY 368
            ..    |:|.||:|||:.|.|||..||.|.|:|||..:|| :.||:.:    |.:.     |:.|
Mouse   297 TAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALPNKAPPTYDTVM-----EMEY 356

  Fly   369 MECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFF 433
            ::.|:.|:|||:|....:.|.|.::..:||:.:||.:.:.|..|.:..|.:|:|.|:.|||:||.
Mouse   357 LDMVLNETLRLYPIANRLERVCKKDVELNGVYIPKGSTVMIPSYALHHDPQHWSEPEEFQPERFS 421

  Fly   434 PENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPV--TLLDDLTFENGIVLR 496
            .||..:..|:.::||..|.|||:|.:||::.:|:.|..:::||...|.  |.:.......|: |:
Mouse   422 KENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKLSRQGL-LQ 485

  Fly   497 TKQNIKVKLVHRE 509
            .::.|.:|:|.|:
Mouse   486 PEKPIVLKVVPRD 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	107/395 (27%)
Cyp3a11	NP_031844.1	CYP3A	67..493	CDD:410743	107/396 (27%)