Protein Alignment Cyp4ac2 and CYP4F8

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 434
• Identity: 141/434 - (32%)
• Similarity: 238/434 - (54%)
• Gaps: 37/434 - (8%)

  Fly    95 PMYNIVRAEEAEEILQSSKLIT-KNMI-YELLKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQ 157
            |:.|:...:....::.:|..|| |::: |:.|||:||:|||:|...||...|:.|||||||.:|:
Human    97 PIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILK 161

  Fly   158 SFLIIFKEECNKLVKVLH---QSVNME----LELNQVIPQFTLNNVCETALGVKLDDLSEGIRYR 215
            .::.||.:..|    ::|   |.:.||    |::.:.|...||:::.:.......:...:...|.
Human   162 PYIKIFSKSAN----IMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYI 222

  Fly   216 QSIHAIEEVMQQRLCNPFF-YNIVYFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQE 279
            .:|..:..::.:| .|.|| |....:||....|:.....::.|:|:..:|::||....|.  |.:
Human   223 TAIMELSALVVKR-NNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQ--GVD 284

  Fly   280 DEFGKKQRYAMLD----TLLAAEADG-QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHED 339
            |....|.:...||    .||:.:.:| ::..:.|..|.:||||.|:|||::.|.:.|..||.|.:
Human   285 DFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPE 349

  Fly   340 VQKKCYEEIKYLPDDS-------DDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVV- 396
            .|::|.:|::.|..|.       ||::     :|.::...:||||||.|.:|...|.|.::.|:
Human   350 YQERCRQEVQELLKDREPKEIEWDDLA-----QLPFLTMCLKESLRLHPPIPTFARGCTQDVVLP 409

  Fly   397 NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFA 461
            :..::||....||:::.|..:...:.:|:::.|.||.|||...|.|.||:|||||.|||||||||
Human   410 DSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFA 474

  Fly   462 ILEIKVLLAAVIRNFKILPVTLLDDLTFENGIVLRTKQNIKVKL 505
            :.|:||:||..:..|:|||.......|.|  ||||.:..:.:::
Human   475 MAEMKVVLALTLLRFRILPDHREPRRTPE--IVLRAEDGLWLRV 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	141/430 (33%)
CYP4F8	NP_009184.1	CYP4F	74..515	CDD:410772	141/431 (33%)