Protein Alignment Cyp4ac2 and cyp4b1.5

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: XP_031756807.1
• Gene: cyp4b1.5 / 100488227
• XenbaseID: XB-GENE-5810927
• Length: 516
• Species: Xenopus tropicalis
• Alignment Length: 536
• Identity: 156/536 - (29%)
• Similarity: 272/536 - (50%)
• Gaps: 83/536 - (15%)

  Fly    11 LVIFIFRKLWAHLNRTYFILSLCKRIRTEDGSLLESKIYVAP-SKTRFGNNFDLVNFTSESIFNF 74
            |::.:::....:|.|.:.:.:|..              :..| |...:||..:......| :...
 Frog    23 LLLVLYKATQLYLKRRFLVAALSP--------------FPGPKSHWLYGNAHEFFQVGKE-LDLI 72

  Fly    75 MRDASAKAKGRNYLWYFFHAPMYNIVRAEEAEEIL--QSSKLITKNMIYELLKPFLGEGLLISTD 137
            :|.|.....|.:.....|||.:: :...:.|:.||  |..|   .:..|:.|.|::|:|||:.:.
 Frog    73 LRWAQVYPYGVSMWLGNFHAALF-VTHPDYAKAILGRQEPK---DDTAYKYLVPWIGKGLLVLSG 133

  Fly   138 QKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLV-----KVLHQSVNMEL-------ELNQVIP- 189
            .||...|:.|||.||:.||:.::.:. .:|.:::     |::....::||       .|:.::.
 Frog   134 PKWFQHRRLLTPGFHYDVLKQYVSLM-SDCTRVMLDKWDKLMPNEKSIELFHHVSLMTLDTIMKC 197

  Fly   190 QFTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEVMQQRLCNPFF--YNIVYFFL--FG-DYRKQ 249
            .|:.|:.|:.         :....|.::::.:..::.:|  :.||  :|.|.|.|  .| .:||.
 Frog   198 AFSYNSSCQN---------NRDNEYIKAVYELSYLVYER--SSFFPYHNDVIFSLSPLGFRFRKA 251

  Fly   250 VNNLKIAHEFSSNIIEKRR-SLFKSNQLGQEDEFGKKQRYAMLDTLLAAEADGQIDHQGICD--- 310
               |.|||:.:..:|:.|: ||....:|   |:..:|:....||.||.|:.:   :.:|:.|
 Frog   252 ---LSIAHQHTDKVIKHRKESLINETEL---DKISQKRHLDFLDILLFAKDE---NGKGLSDEDL 307

  Fly   311 --EVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNELVYMECVI 373
              ||:||||.|:|||::.:.:.|..:|.:.:.|:||.|||..|..|.:.:......::.|....|
 Frog   308 RAEVDTFMFAGHDTTASGISWILYCIAKYPEHQQKCREEITELLGDRETMEWGDLGQIPYTTSCI 372

  Fly   374 KESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQPDRFFPEN 436
            ||||||:|.||.|||| :.:.:.  :|..:|:.|::...:|.|.|....:.:|::|.|.||.|||
 Frog   373 KESLRLYPPVPIIGRR-LSKSITFSDGRSLPEGTEVITSIYAINRSPSVWKDPEVFDPSRFSPEN 436

  Fly   437 TVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILPVTLLDDLTFEN------GIVL 495
            :.:|||.||:|||||.||||||.||:.|:||::|..::.:::.|..       :|      .|||
 Frog   437 SDSRHPHAFIPFSAGPRNCIGQNFAMNEMKVVVALTLQRYELFPDP-------DNKPQKVPQIVL 494

  Fly   496 RTKQNIKVKLVHRENK 511
            |:...|.||:...|.|
 Frog   495 RSLNGINVKIRRVEKK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	141/452 (31%)
cyp4b1.5	XP_031756807.1	CYP4B-like	69..503	CDD:410771	143/466 (31%)