Protein Alignment Cyp4ac2 and Cyp3a41b

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001098629.1
• Gene: Cyp3a41b / 100041375
• MGIID: 3714859
• Length: 504
• Species: Mus musculus
• Alignment Length: 430
• Identity: 115/430 - (26%)
• Similarity: 215/430 - (50%)
• Gaps: 42/430 - (9%)

  Fly   108 ILQSSKLITKNMIYELLKPF-----------LGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLI 161
            ::...::|...::.|....|           :.:.:.||.|::|...|..|:|.|....|:....
Mouse    83 VITDPEMIKNVLVKECFSVFTNRREFGPVGIMSKAISISKDEEWKRYRALLSPTFTSGKLKEMFP 147

  Fly   162 IFKEECNKLVKVLHQSV--NMELELNQVIPQFTLNNVCETALGVKLDDLSEGIRYRQSIHAIEEV 224
            :.::..:.|||.|.|..  ...:.:..|:..::::.:..|:.||.:|.|:.  .....:...:.:
Mouse   148 VIEQYGDILVKYLMQEAEKGKPVTMKDVLGAYSIDVITSTSFGVNVDSLNN--PEDPFVEKAKGI 210

  Fly   225 MQQRLCNPFFYNIVYF-FLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRY 288
            ::....:|..:::|.| ||...|  ::.|:.:..:.|....:|..:..|.::|..:    :|.|.
Mouse   211 LRVDFFDPLVFSVVLFPFLTPVY--EMLNICMFPKDSIEFFKKFVNRMKESRLDSK----QKHRV 269

  Fly   289 AMLDTLLAA--EADGQIDHQGICD-EVN----TFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYE 346
            ..|..::.|  .:..:..|:.:.| |:.    .|:|.||:|||:.|.|||..||.|.|:|||..|
Mouse   270 DFLQLMMNAHNNSKDKDSHKALSDMEITAQSIVFIFAGYETTSSTLSFTLYCLATHPDIQKKLQE 334

  Fly   347 EI-KYLPDDS----DDISVFQFNELVYMECVIKESLRLFPSVPFIGRRCVEEGVVNGLIMPKNTQ 406
            || :.||:.:    |.:.     |:.|::.|:.|:|||:|....:.|.|.::..:||:.:||.:.
Mouse   335 EIDETLPNKAPPTYDTVM-----EMEYLDMVLNETLRLYPIGNRLERFCKKDVELNGVYIPKGST 394

  Fly   407 INIHLYEIMRDARHFSNPKMFQPDRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAA 471
            :.|..|.:..|.:|:..|:.|||:||..||..:..|:.::||..|.|||||.:||.:.:|:.|..
Mouse   395 VMIPSYALHHDPQHWPEPEEFQPERFSKENKGSIDPYLYMPFGIGPRNCIGMRFAFMTMKLALTK 459

  Fly   472 VIRNFKILPV--TLLDDLTFENGIVLRTKQNIKVKLVHRE 509
            |::||...|.  |.:.......|: |:.::.|.:|:|.|:
Mouse   460 VMQNFSFQPCQETQIPLKLSRQGL-LQPEKPIVLKVVPRD 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	112/422 (27%)
Cyp3a41b	NP_001098629.1	CYP3A	67..493	CDD:410743	112/423 (26%)