Protein Alignment Cyp4ac2 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_608917.3
• Gene: Cyp4ac2 / 33755
• FlyBaseID: FBgn0031694
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 532
• Identity: 149/532 - (28%)
• Similarity: 245/532 - (46%)
• Gaps: 112/532 - (21%)

  Fly    51 APSKTRFGNNFDLVNFTSESIFNFMRDAS--------AKA----KGRNYL-------------WY 90
            |.|.|||          ::|:..|::.||        .||    ..|.:|             |:
Mouse     5 ALSPTRF----------ADSLSGFLQVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWF 59

  Fly    91 FFHAPMYNIVRAEEAEEILQ---------------SSKLIT-----------------KNMIYEL 123
            |.|.....   .:|.:|::.               |:..:|                 .|.||.|
Mouse    60 FGHEQFKG---EQELKEVVSCIEHFPSAFPCWFWGSNAYLTVYDPDYMKVILGRSDPKANGIYRL 121

  Fly   124 LKPFLGEGLLISTDQKWHSRRKALTPAFHFKVLQSFLIIFKEECNKLVKVLHQSVNM-------- 180
            |.|::|.|||:...|.|...|:.||||||:.:|:.:           ||.:..|:.:
Mouse   122 LAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILKPY-----------VKNMADSIRLMLDKWERL 175

  Fly   181 -----ELELNQVIPQFTLNNVCETALGVKLDDLSEG--IRYRQSIHAIEEVMQQRLCNPFFYNIV 238
                 .:|:.|.|...||:.|.:.|...|.....:|  ..|.|:|..:..:...|:.|.|..|..
Mouse   176 AGQDSSIEIFQHISLMTLDTVMKCAFSHKGSVQVDGNYKTYLQAIGDLNNLFHSRVRNIFHQNDT 240

  Fly   239 YFFLFGDYRKQVNNLKIAHEFSSNIIEKRRSLFKSNQLGQEDEFGKKQRYAMLDTLLAA--EADG 301
            .:.|..:.|......::||:.:..:|:.|:...:..  |:.:...||:|...||.||.|  |...
Mouse   241 IYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDE--GELENIKKKRRLDFLDILLFARMENGD 303

  Fly   302 QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEIKYLPDDSDDISVFQFNEL 366
            .:..:.:..||:||||||:|||::.:.:....||.|.:.|::|.||::.|..|...|:....:::
Mouse   304 SMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPEHQQRCREEVQSLLGDGSSITWDHLDQI 368

  Fly   367 VYMECVIKESLRLFPSVPFIGRRCVEEGVV--NGLIMPKNTQINIHLYEIMRDARHFSNPKMFQP 429
            .|....|||:|||:|.||.|.|. :...|.  :|..:||..|:.:.:|.:..:.:.:.||::|.|
Mouse   369 PYTTMCIKEALRLYPPVPGIVRE-LSTSVTFPDGRSLPKGVQVTLSIYGLHHNPKVWPNPEVFDP 432

  Fly   430 DRFFPENTVNRHPFAFVPFSAGQRNCIGQKFAILEIKVLLAAVIRNFKILP-VTLLDD------L 487
            .||.|::.  ||..:|:|||.|.|||||::||:.|:||::|..:.:|::|| .|.:.:      |
Mouse   433 SRFAPDSP--RHSHSFLPFSGGARNCIGKQFAMSELKVIVALTLLHFELLPDPTRVPEPLARIVL 495

  Fly   488 TFENGIVLRTKQ 499
            ..:|||.|..|:
Mouse   496 KSKNGIYLHLKK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac2	NP_608917.3	CYP4	84..503	CDD:410721	138/487 (28%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	130/448 (29%)