Protein Alignment Cyp4ac1 and CYP4F2

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001073.3
• Gene: CYP4F2 / 8529
• HGNCID: 2645
• Length: 520
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 160/528 - (30%)
• Similarity: 268/528 - (50%)
• Gaps: 50/528 - (9%)

  Fly     2 WIALLGI---PILLAVL---TLLLKHINK-TYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNN 59
            |:.|..:   |.||.:|   :.||.|:.. ||......:|:|... .|        |.:..|..:
Human     8 WLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFP-QP--------PRRNWFWGH 63

  Fly    60 LDILNFTPASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLIT--KNVVYEL 122
            ..::|.|...:....:......:|.. :|....:|:.::..|:....|..::..|.  ....|..
Human    64 QGMVNPTEEGMRVLTQLVATYPQGFK-VWMGPISPLLSLCHPDIIRSVINASAAIAPKDKFFYSF 127

  Fly   123 IRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKN---LDAE---- 180
            :.|:||||||:|...||...|:.||||||||:|:.::.||.|.    :|::...   |.:|
Human   128 LEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNES----VNIMHAKWQLLASEGSAC 188

  Fly   181 LELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDY 245
            |::.:.|...||:::.:...........:.:||..||..:..::.:|....|::.::.:::..|.
Human   189 LDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEILLHIDFLYYLTPDG 253

  Fly   246 RKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEF-GRKQRYAMLD----TLLAAEADG-QIDH 304
            ::..:..|:||||:..:|:.:|:....:   .||:| ..|.:...||    .||:.:.|| ::..
Human   254 QRFRRACRLVHDFTDAVIQERRRTLPSQ---GVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSD 315

  Fly   305 QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSD--DISMFQFNKLVY 367
            :.|..|.:||||||:|||::.|.:.|..||.|.:.|::|.:||:.|.:|.:  :|.......|.:
Human   316 EDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPF 380

  Fly   368 LECVIKESLRMFPSVPFIGRQCVEETVV-NGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRF 431
            |...:|||||:.|.||.|.|...::.|: :|.|:||.....|.::....:|..:|.|:::.|.||
Human   381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF 445

  Fly   432 LPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLED-------LTFE 489
            .|||...|.|.|::|||||.||||||.||:.||||:||..:..|::|| ...|.       |..|
Human   446 DPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLP-DHTEPRRKPELVLRAE 509

  Fly   490 NGIVLRTQ 497
            .|:.||.:
Human   510 GGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	142/440 (32%)
CYP4F2	NP_001073.3	CYP4F	74..515	CDD:410772	140/449 (31%)