Protein Alignment Cyp4ac1 and Cyp4f18

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_077764.2
• Gene: Cyp4f18 / 72054
• MGIID: 1919304
• Length: 524
• Species: Mus musculus
• Alignment Length: 526
• Identity: 156/526 - (29%)
• Similarity: 259/526 - (49%)
• Gaps: 57/526 - (10%)

  Fly     2 WIALL--GIPILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILN 64
            |:.||  |...|||.:      :...|.:...:.|:|.....|..:.:.         .:|.::.
Mouse    19 WLLLLLAGASCLLAYI------LTPIYGVFENSLRLRCFPQPPKRNWIL---------GHLGLIQ 68

  Fly    65 FTPASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVR---PEEAEEVFQSTKLIT--KNVVYELIR 124
            .:...:...  :|..:.......|:  ..|::.|:|   |...:.|..:..|:.  ..|.|..::
Mouse    69 SSEEGLLYI--QSLVRTFRDACCWW--VGPLHPVIRIFHPAFIKPVVLAPALVAPKDTVFYRFLK 129

  Fly   125 PFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECK----KFLNVLEKNLDAELELNQ 185
            |:||||||:||..||...|:.||||||||:|:.::.:|.:...    |:..:..|. .|.|.:.:
Mouse   130 PWLGDGLLMSTGDKWSRHRRMLTPAFHFNILKPYVKVFNDSTNIMHAKWQRLASKG-SAYLNMFE 193

  Fly   186 VIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQ 250
            .|...||:::.:.......:...:.:||..||..:..::.:|....|::.:.::::..|..:..:
Mouse   194 HISLMTLDSLQKCVFSFDSNCQEKPSEYITAILELSTLVARRHQRLLLHVDLFYYLTHDGMRFRK 258

  Fly   251 NLRIVHDFSSRII-ERKRQQFQQKQLGEVDEFGRKQRYAMLD----TLLAAEADGQ-IDHQGICD 309
            ..|:||||:..:| ||:|....|   |.||....|.:...||    .||:.:..|: :..:.|..
Mouse   259 ACRLVHDFTDAVIRERRRTLLDQ---GGVDVLKAKAKAKTLDFIDVLLLSKDEHGKALSDEDIRA 320

  Fly   310 EVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPED--SDDISMFQFNKLVYLECVI 372
            |.:||||.|:|||::.|.:.|..||.|.:.|::|.:||..|..|  .::|......:|.:|...|
Mouse   321 EADTFMFGGHDTTASGLSWILYNLARHPEYQERCRQEVRELLRDREPEEIEWDDLAQLPFLTMCI 385

  Fly   373 KESLRMFPSVPFIGRQCVEETVV-NGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENT 436
            |||||:.|.|..|.|.|.::.|: :|.|:||.....|.|:....:|..:|.|:::.|.||..:|.
Mouse   386 KESLRLHPPVTAISRCCTQDIVLPDGRVIPKGVISRISIFGTHHNPAVWPDPEVYDPFRFDADNV 450

  Fly   437 VNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLED----------LTFENG 491
            ..|.|.|::|||||.||||||.||:.||||.||..:..|::||    :|          |..|.|
Mouse   451 KGRSPLAFIPFSAGPRNCIGQTFAMSEMKVALALTLLRFRVLP----DDKEPRRKPELILRAEGG 511

  Fly   492 IVLRTQ 497
            :.|:.:
Mouse   512 LWLKVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	143/443 (32%)
Cyp4f18	NP_077764.2	CYP4F	74..515	CDD:410772	143/452 (32%)