Protein Alignment Cyp4ac1 and CYP4F11

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_067010.3
• Gene: CYP4F11 / 57834
• HGNCID: 13265
• Length: 524
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 158/528 - (29%)
• Similarity: 267/528 - (50%)
• Gaps: 50/528 - (9%)

  Fly     2 WIAL---LGIPILLAVLT----LLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNN 59
            |:.|   ...|.||.:|.    ||.:.:..||......:|::.....|.::         .|..:
Human     8 WLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQN---------WFWGH 63

  Fly    60 LDILNFTPASVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKN--VVYEL 122
            ..::..|...:....:..|...:|.. ||.....|:..:..|:....:..::..:...  :.|..
Human    64 QGLVTPTEEGMKTLTQLVTTYPQGFK-LWLGPTFPLLILCHPDIIRPITSASAAVAPKDMIFYGF 127

  Fly   123 IRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNV-------LEKNLDAE 180
            ::|:||||||:|...||...|:.||||||||:|:.::.||    .|.:|:       |.....|.
Human   128 LKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIF----NKSVNIMHDKWQRLASEGSAR 188

  Fly   181 LELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDY 245
            |::.:.|...||:::.:.....:.:...:.:||..||..:...:.:|....|::.::.:::..|.
Human   189 LDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDG 253

  Fly   246 RKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEF-GRKQRYAMLD----TLLAAEADG-QIDH 304
            ::..:...:||||:..:|:.:|.....:   .:|:| ..|.:...||    .||:.:.|| ::..
Human   254 QRFRRACHLVHDFTDAVIQERRCTLPTQ---GIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSD 315

  Fly   305 QGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSD--DISMFQFNKLVY 367
            :.|..|.:||||||:|||::.|.:.|..||.|.:.|::|.:||:.|.:|.:  :|......:|.:
Human   316 EDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPF 380

  Fly   368 LECVIKESLRMFPSVPFIGRQCVEETVV-NGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRF 431
            |...||||||:.|.||.|.|.|.::.|: :|.|:||.....|:|..|..:|..:|.|:::.|.||
Human   381 LTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRF 445

  Fly   432 LPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLED-------LTFE 489
            ..||...|.|.|::|||||.||||||.||:.||||:||..:.:|::|| |..|.       |..|
Human   446 DQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILP-THTEPRRKPELILRAE 509

  Fly   490 NGIVLRTQ 497
            .|:.||.:
Human   510 GGLWLRVE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	143/440 (33%)
CYP4F11	NP_067010.3	CYP4F	74..515	CDD:410772	142/449 (32%)