Protein Alignment Cyp4ac1 and cyp-25A3

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001040850.1
• Gene: cyp-25A3 / 4363046
• WormBaseID: WBGene00014697
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 558
• Identity: 129/558 - (23%)
• Similarity: 227/558 - (40%)
• Gaps: 121/558 - (21%)

  Fly    10 ILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRF--GNNLDILNFTPASVFN 72
            ||.::|..|:..|  .|.||:..:|.|      |..|:.:...:..:  ||...|:.
 Worm     5 ILTSILVSLVSFI--IYVILARKERFR------LRGKIGLSGPEPHWLMGNLKQIIE-------- 53

  Fly    73 FVRESTAKAK---GQNYLWYFLYAPMY--------------NVVRPEEAEEVF----------QS 110
                  .|||   ..:|.||......:              |:...|:.:|||          ..
 Worm    54 ------RKAKLGYDDSYDWYNKLHKQFGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTP 112

  Fly   111 TKLITKNVVYELIRPFLGDGLLIST-DHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLE 174
            ..:|..|.        |.:.||.:| :..|...|.|:.|.|....:::.......:...||.:|:
 Worm   113 PPIIEDNK--------LKESLLQNTYESGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILK 169

  Fly   175 KNLDAELELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYF 239
            :...:..:.          :|.:...|:.||.:.      |...||:. ..||..|.:.|.|
 Worm   170 EKASSGQKW----------DIYDDFQGLTLDVIG------KCAFAIDS-NCQRDRNDVFYVN--- 214

  Fly   240 FVYGDYRKHLQNLRIVHDFSSRIIE------------RKRQQFQQKQLGEV-------DEFGRKQ 285
                 .||.:.|:.|.|   |:||.            :...:|......|:       |.:.|::
 Worm   215 -----ARKFITNIDIRH---SKIISTSFLFPELSKLWKVLYRFTDLAKAEIPLVEGLADVYERRR 271

  Fly   286 ------RYAMLDTLLAAEADGQ--IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKK 342
                  ...:|..||..|.|..  :..|.:.:....|:..||:||||.:.:...:|:.:.:||:|
 Worm   272 GGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQK 336

  Fly   343 CYEEVENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSV-PFIGRQCVEETVVNGMVMPKDTQI 406
            .|||:....|:. .::....:.:.||:.|.||:||.:|.| .|..|:|:::..:.|...||...:
 Worm   337 LYEEIMEAKENG-GLTYDSIHNMKYLDYVYKETLRCYPPVIHFSNRRCLKDITIRGQFYPKGAIV 400

  Fly   407 SIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNR-HPFAYVPFSAGQRNCIGQKFAILEMKVLLAA 470
            ....:.:.|:|.::..|:.|.|:||  ||...: ....::||..|.|.|:|.:||.:|.|..:|.
 Worm   401 VCLPHTVHRNPENWDSPEEFHPERF--ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAK 463

  Fly   471 VIRNFKLLPATQLEDLTFE-NGIVLRTQENIKVKLSKR 507
            ::..|:|.......||..: ||:::|.::.:::.|..|
 Worm   464 LLDTFELKQFEGEADLIPDCNGVIMRPKDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	109/473 (23%)
cyp-25A3	NP_001040850.1	CYP3A-like	73..495	CDD:410678	106/460 (23%)