Protein Alignment Cyp4ac1 and Cyp12a4

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_650783.2
• Gene: Cyp12a4 / 42294
• FlyBaseID: FBgn0038681
• Length: 536
• Species: Drosophila melanogaster
• Alignment Length: 489
• Identity: 106/489 - (21%)
• Similarity: 201/489 - (41%)
• Gaps: 95/489 - (19%)

  Fly    43 LESKVAIMPGKTRFGNNLDILNFTPASVFNFVRESTAKAKGQNYLWYFLY------APMYNVVRP 101
            |..|:::..||.:   |::::     .:|..:|        |:|...|..      .|..:...|
  Fly    58 LSMKMSMPGGKYK---NMELM-----EMFEAMR--------QDYGDIFFMPGIMGNPPFLSTHNP 106

  Fly   102 EEAEEVFQSTKLITK-----NVVY--ELIRPFLGDGLL--ISTDHK-WHSRRKALTPA------- 149
            ::.|.||::..:...     .::|  |..|.....|::  |.|..| |...|..:.|.
  Fly   107 QDFEVVFRNEGVWPNRPGNYTLLYHREEYRKDFYQGVMGVIPTQGKPWGDFRTVVNPVLMQPKNV 171

  Fly   150 -FHFNVLQSFLGIFKEECKKFLNVLEKN-LDAELELNQVIPPFTLNNICETALGVKLDDMSEGN- 211
             .::..:..   :.:|..::.|.:.:.: |:|..:....|..:||.::...||..:|..:...|
  Fly   172 RLYYKKMSQ---VNQEFVQRILELRDPDTLEAPDDFIDTINRWTLESVSVVALDKQLGLLKNSNK 233

  Fly   212 --EYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVHD----FSSRIIER----- 265
              |..|..|.::|..|..:...:....|.:......::.::.|..:.:    :....|||
  Fly   234 ESEALKLFHYLDEFFIVSIDLEMKPSPWRYIKTPKLKRLMRALDGIQEVTLAYVDEAIERLDKEA 298

  Fly   266 ----KRQQFQQKQLGEVDEFGRKQRYAM-LDTLLAAEADGQIDHQGICDEVNTFMFEGYDTTSTC 325
                .|.:.:|..|.::.:..||....| :|.|:|                      |.||||:.
  Fly   299 KEGVVRPENEQSVLEKLLKVDRKVATVMAMDMLMA----------------------GVDTTSST 341

  Fly   326 LIFTLLMLALHEDVQKKCYEEV-ENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGRQC 389
            ....||.||.:.:.|.:..||| :.||..:.:.:......:.||...||||.|:.|.:....|..
  Fly   342 FTALLLCLAKNPEKQARLREEVMKVLPNKNSEFTEASMKNVPYLRACIKESQRLHPLIVGNARVL 406

  Fly   390 VEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFL----------PENTV-NRHPFA 443
            ..:.|::|..:|..|.::|...:.:....:||:...|.|:|:|          |.|.: :.:||.
  Fly   407 ARDAVLSGYRVPAGTYVNIVPLNALTRDEYFPQASEFLPERWLRSPKDSESKCPANELKSTNPFV 471

  Fly   444 YVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKL 477
            ::||..|.|.|:|::...:|:::..|.:||||.:
  Fly   472 FLPFGFGPRMCVGKRIVEMELELGTARLIRNFNV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	99/449 (22%)
Cyp12a4	NP_650783.2	CYP24A1-like	82..528	CDD:410677	100/457 (22%)