Protein Alignment Cyp4ac1 and cyp46a1.2

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_956755.3
• Gene: cyp46a1.2 / 393433
• ZFINID: ZDB-GENE-040426-1184
• Length: 501
• Species: Danio rerio
• Alignment Length: 555
• Identity: 131/555 - (23%)
• Similarity: 238/555 - (42%)
• Gaps: 116/555 - (20%)

  Fly     2 WIALLGIPILLAVLT------LLLKHINKTY----------FIL----SLTKRVRTEDGSPLESK 46
            ||..:...:|.||.|      |.:.|:::.|          |:|    ||||.:.::|
Zfish     5 WILYIIFYLLSAVFTAFLAYCLYIHHLHQKYDHIPGPPRDNFLLGHSPSLTKAMYSDD------- 62

  Fly    47 VAIMPGKTRFGNNLDILNFTPASVFN--FVRESTAKAKGQNYLWYFLYAPMYNVVR--------- 100
                                  |:.:  |::            |...|.|:|.:..
Zfish    63 ----------------------SLIHDLFLQ------------WAEQYGPVYRINTLHYIAIVVH 93

  Fly   101 -PEEAEEVFQSTKLITKNVVYELI-----RPFLGDGLLISTDHK-WHSRRKALTPAFHFNVLQSF 158
             ||..:.:..|.|.......|..:     :.|||:||:.:.||. |:.:|:.:.|||..:.|:|.
Zfish    94 CPEATKTILMSPKYAKDPFSYSRLFNLFGKRFLGNGLVTAVDHDIWYRQRRIMDPAFSSSYLRSL 158

  Fly   159 LGIFKEECKKFLNVLEK--NLDAELELNQVIPPFTLNNICETALGVKLDDMSE-GNEYRKAIHAI 220
            :..|.|..::.::.||:  |......::.::...||:.||:.|.||.|:.::: .:.::.|:...
Zfish   159 ISTFDEMSERLMDKLEEMANNKTPAVMHDLVNCVTLDVICKVAFGVDLNFLAQKDSPFQNAVELC 223

  Fly   221 EEVLIQRVCNPLMYY---NWYFFVYGDYRKHLQNLRIVHDFSSRIIERKR-QQFQQKQLGEVDEF 281
            ...:.....:||...   ||         |.:|.:|     .:.::.||. :::.|.:...|...
Zfish   224 LNGMALDARDPLFRIFPKNW---------KLIQQIR-----DAAVLLRKTGEKWIQNRKTAVKNG 274

  Fly   282 GRKQRYAMLDTLLAAE---ADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKC 343
            ....:..:...|..||   .:...|.:.:.|...||...|.:||:..|.|.::.|..:.::.|:.
Zfish   275 EDVPKDILTQILKIAEEENVNSSEDLEQMMDNFVTFFIAGQETTANQLSFAIMALGRNPEIYKRA 339

  Fly   344 YEEVENLPEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISI 408
            ..||:.:.....:||.....||.||..|:||:||::|:.|...|...|:.::||:.:|....:..
Zfish   340 KAEVDEVLGTKREISNEDLGKLTYLSQVLKETLRLYPTAPGTNRWLHEDMIINGIKIPGGCSVMF 404

  Fly   409 HIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIR 473
            ..:...|..:.|..|..|.|:|| .||....: :.|.||:.|.|.|:||.|:.:|.||:||.:::
Zfish   405 SSFVSQRLEKFFKDPLKFDPERF-DENAPKPY-YCYYPFALGPRTCLGQVFSQMEAKVVLAKLLQ 467

  Fly   474 NFK--LLPATQLE-----DLTFENGIVLRTQENIK 501
            .|:  |:|....:     .|..::|::.    |||
Zfish   468 RFEFSLVPGQSFDIKDTGTLRPKSGVIC----NIK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	113/452 (25%)
cyp46a1.2	NP_956755.3	None