Protein Alignment Cyp4ac1 and Cyp3a23-3a1

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_037237.2
• Gene: Cyp3a23-3a1 / 25642
• RGDID: 628626
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 470
• Identity: 120/470 - (25%)
• Similarity: 207/470 - (44%)
• Gaps: 89/470 - (18%)

  Fly    85 NY---LWYF------LYAPMYNVVRPEEAEEVFQSTKLITKNVVYELIRPF-----------LGD 129
            ||   ||.|      .|..::.:...:........|::|...:|.|....|           :|.
  Rat    52 NYYMGLWKFDVECHKKYGKIWGLFDGQMPLFAITDTEMIKNVLVKECFSVFTNRRDFGPVGIMGK 116

  Fly   130 GLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAELELNQVIPPFTLNN 194
            .:.:|.|.:|...|..|:|.|....|:....:.::.....:..|.:.....:.:.:|...::::.
  Rat   117 AISVSKDEEWKRYRALLSPTFTSGRLKEMFPVIEQYGDILVKYLRQEKGKPVPVKEVFGAYSMDV 181

  Fly   195 ICETALGVKLDDMSEGNE--YRKA-----IHAIEEVLIQRVCNPLM--YYNW------------Y 238
            |..|:.||.:|.::...:  ..||     |...:.:.:..|..|.:  .|..            :
  Rat   182 ITSTSFGVNVDSLNNPKDPFVEKAKKLLRIDFFDPLFLSVVLFPFLTPVYEMLNICMFPKDSIEF 246

  Fly   239 F--FVYGDYRKHLQNLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAEADGQ 301
            |  |||......|.:           :::.|..|.|..:...::...|:.:..|       :|.:
  Rat   247 FKKFVYRMKETRLDS-----------VQKHRVDFLQLMMNAHNDSKDKESHTAL-------SDME 293

  Fly   302 IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVEN-LPEDSD---DISMFQF 362
            |..|.|     .|:|.||:.||:.|.|.|..||.|.|.|||..||::. ||..:.   |..|
  Rat   294 ITAQSI-----IFIFAGYEPTSSTLSFVLHSLATHPDTQKKLQEEIDRALPNKAPPTYDTVM--- 350

  Fly   363 NKLVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQ 427
             ::.||:.|:.|:||::|....:.|.|.::..:||:.|||.:.:.|..|.:.|||:|:|:|:.|:
  Rat   351 -EMEYLDMVLNETLRLYPIGNRLERVCKKDVEINGVFMPKGSVVMIPSYALHRDPQHWPEPEEFR 414

  Fly   428 PDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGI 492
            |:||..||..:..|:.|:||..|.|||||.:||::.||:.|..|::||...|..:.:
  Rat   415 PERFSKENKGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALTKVLQNFSFQPCKETQ-------- 471

  Fly   493 VLRTQENIKVKLSKR 507
                   |.:|||::
  Rat   472 -------IPLKLSRQ 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	117/463 (25%)
Cyp3a23-3a1	NP_037237.2	CYP3A	67..491	CDD:410743	115/455 (25%)