Protein Alignment Cyp4ac1 and Cyp4a2

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001038235.1
• Gene: Cyp4a2 / 24306
• RGDID: 2479
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 519
• Identity: 146/519 - (28%)
• Similarity: 259/519 - (49%)
• Gaps: 63/519 - (12%)

  Fly    11 LLAVLTLLLK----HINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFT----- 66
            ||::..:|.|    ::.:.:.:.:|.|...|             |....:|:||....|.
  Rat    24 LLSLFLVLFKAVQFYLRRQWLLKALEKFPST-------------PSHWLWGHNLKDREFQQVLTW 75

  Fly    67 ----PASVFNFVRESTAKAKGQNYLWYFLYAPMY-NVVRPEEAEEVFQSTKLITKNVVYELIRPF 126
                |.:...::..|||:.        .||.|.| .||......:.:||            :.|:
  Rat    76 VEKFPGACLQWLSGSTARV--------LLYDPDYVKVVLGRSDPKPYQS------------LAPW 120

  Fly   127 LGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEK--NLDAELELNQVIPP 189
            :|.|||:....||...|:.||||||:::|:.::.|..:.....|:..||  :.|..||:...:..
  Rat   121 IGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSL 185

  Fly   190 FTLNNICETAL----GVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQ 250
            .||:.:.:.|.    .|:||..|  ..|.||:..:..::..||.:.....:..:.:..|.|...:
  Rat   186 MTLDTVMKCAFSHQGSVQLDVNS--RSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRR 248

  Fly   251 NLRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRYAMLDTLLAAE-ADGQ-IDHQGICDEVNT 313
            ..:|.|:.:..:|:.::.|.|.::  |:.:..:|:....||.||.|: .||: :..:.:..||:|
  Rat   249 ACQIAHEHTDGVIKTRKAQLQNEE--ELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDT 311

  Fly   314 FMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQFNKLVYLECVIKESLRM 378
            |||||:|||::.:.:....||.|.:.|::|.|||:::..|...::....:::.|....|||:||:
  Rat   312 FMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRL 376

  Fly   379 FPSVPFIGRQCVEE-TVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPF 442
            :..||.:.|:.... |..:|..:||..:::|.||.:..:|.::|.|.:|.|.||.|::.  ||..
  Rat   377 YSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSP--RHSH 439

  Fly   443 AYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFENGIVLRTQENIKVKLSK 506
            ||:|||.|.|||||::||:.|:||.:|..:..|:|||......:.... :||:::..|.::|.|
  Rat   440 AYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPR-LVLKSKNGIHLRLKK 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	128/428 (30%)
Cyp4a2	NP_001038235.1	CYP4B-like	69..499	CDD:410771	133/456 (29%)