Protein Alignment Cyp4ac1 and cyp-13A12

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 129/549 - (23%)
• Similarity: 222/549 - (40%)
• Gaps: 148/549 - (26%)

  Fly    10 ILLAVLTLLLKHINKTYFILSLTKR--VRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPASVFN 72
            |.||:||.::..::...:..|..||  :....|.|:            .|:.|::|:
 Worm     4 IFLAILTSIIGVLSFYLWTWSYWKRRGIAGPSGYPI------------LGSALEMLS-------- 48

  Fly    73 FVRESTAKAKGQNYL----WYFLYAPMYNVVR----------PEEAEEVFQSTKLITKNVVYELI 123
                    ::...||    |...|..:|.:..          |:..:|||...   ..|.....:
 Worm    49 --------SENPPYLQLKEWTKQYGKVYGITEGLSRTLVISDPDLVQEVFVKQ---YDNFFGRKL 102

  Fly   124 RPFLGD-------GLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECK-KFLNVLEKNLDA- 179
            .|..||       .|..|..|:|...|...:|.|..|.|:. |....|||. :.|..:|::.|.
 Worm   103 NPIQGDPNKDKRVNLFSSQGHRWKRLRTISSPTFSNNSLRK-LKTTVEECAVELLRHIEQHTDGG 166

  Fly   180 -ELELNQVIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYG 243
             .::|......|||:.|...|:|.....|.:                    |||:.|  ...|:|
 Worm   167 QPIDLLDFYQEFTLDVIGRIAMGQTDSQMFK--------------------NPLLPY--VRAVFG 209

  Fly   244 DYRKHL-------------------------QN--LRIVHDFSSRIIERKRQQFQQKQLGEVDEF 281
            :.||.|                         :|  :.::...|:.:.:|.:.:...::.| :|.
 Worm   210 EPRKGLFLSGSLAPWIGPILRMVMFSLPNIVKNPAVHVIRHTSNAVEQRVKLRMADEKAG-IDP- 272

  Fly   282 GRKQRYAMLDTLLAAEADG------------------QIDHQGICDEVNTFMFEGYDTTSTCLIF 328
            |..|.:  :|..|.|::|.                  |:..:.|..:...|:..|:|||:..|.:
 Worm   273 GEPQDF--IDLFLDAKSDDVELENNEDFTKAGVKVTRQLTTEEIVGQCFVFLIAGFDTTALSLSY 335

  Fly   329 TLLMLALHEDVQKKCYEEVENLPEDSD-DISMFQFNKLVYLECVIKESLRMFPSVPFIG-----R 387
            :..:||.|..||||..||::.  |.:| :::..|.:||.|:||||||:|||:|    :|     |
 Worm   336 SSFLLATHPKVQKKLQEEIDR--ECADPEVTFDQLSKLKYMECVIKETLRMYP----LGALANSR 394

  Fly   388 QCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPK-PDLFQPDRFLPENTVNRHPF---AYVPFS 448
            .|:..|.:....:.:.|.|....:.:..|...:.: .:.|:|:|:   .:.:.|.:   .|:||.
 Worm   395 CCMRATKIGNYEIDEGTNILCDTWTLHSDKSIWGEDAEEFKPERW---ESGDEHFYQKGGYIPFG 456

  Fly   449 AGQRNCIGQKFAILEMKVLLAAVIRNFKL 477
            .|.|.|||.:.|.:|.|:||:.::|.:.|
 Worm   457 LGPRQCIGMRLAYMEEKLLLSHILRKYTL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	116/474 (24%)
cyp-13A12	NP_499705.1	CYP3A-like	63..507	CDD:410678	113/462 (24%)