Protein Alignment Cyp4ac1 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 127/547 - (23%)
• Similarity: 227/547 - (41%)
• Gaps: 99/547 - (18%)

  Fly    12 LAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIM-PGKTRFGNNL-------DILNFTPA 68
            |.:|:.|:..|...:..:.|.:|.|.:    |..|:.:. |....|..||       :.|.:..|
 Worm     3 LLILSSLVISIFTFFIYIILARRERFK----LREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDA 63

  Fly    69 S-VFNFVRESTAKAKGQNYLWYFLYAPMYNVV--RPEEAEEVF--QSTKLITKNV--VYELIRPF 126
            : .||.:.|...:..|      ..|....|:|  ..::.:|||  ..:....::|  :|| ....
 Worm    64 NRWFNELHEQYGETFG------IYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIYE-ANQL 121

  Fly   127 LGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAELELNQVIPPFT 191
            ....|:.|....|...|.|:.|.|....:::.......:...||::|.:...:..:.
 Worm   122 TASLLMNSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKW-------- 178

  Fly   192 LNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNLRIVH 256
              :|.:...|:.||.:.      |...||:. ..||..|.:.|.|        .:|::.|:.|.|
 Worm   179 --DIYDDFQGLTLDVIG------KCAFAIDS-NCQRDRNDVFYVN--------AKKYISNIDIRH 226

  Fly   257 ---------------------------DFSSRIIERKRQQFQQKQLGE----VDEFGRKQRYAML 290
                                       |....::|.....:::::.||    ||         :|
 Worm   227 SKIIAASVLLPELSTFWKALYKYTPLADAEIPLVEGLSNVYERRRGGEGSDSVD---------LL 282

  Fly   291 DTLLAAEADGQ--IDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPED 353
            ..||..|.|..  :..|.:.:....|:..||:||||.:.:...:|:.:.:||:|.|||:....|:
 Worm   283 KLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKEN 347

  Fly   354 SDDISMFQFNKLVYLECVIKESLRMFPSV-PFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDP 417
            . .::....:.:.||:||.||:||.:|.| .||.|.|.|:..:.|...||...:....:.:.|:|
 Worm   348 G-GLTYDSIHNMKYLDCVYKETLRFYPPVIHFIRRLCREDITIRGQFYPKGAIVVCLPHTVHRNP 411

  Fly   418 RHFPKPDLFQPDRFLPENTVNR-HPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPAT 481
            .::..|:.|.|:||  ||...: ....::||..|.|.|:|.:||.:|.|..:..::..|:|....
 Worm   412 ENWDSPEEFHPERF--ENWEEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFE 474

  Fly   482 QLEDLTFE-NGIVLRTQENIKVKLSKR 507
            ...||..: ||:::|..:.:::.|..|
 Worm   475 GEADLIPDCNGVIMRPNDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	107/460 (23%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	107/465 (23%)