Protein Alignment Cyp4ac1 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 122/538 - (22%)
• Similarity: 226/538 - (42%)
• Gaps: 63/538 - (11%)

  Fly     4 ALLGIPILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPA 68
            |::.:.:|.|.:....|.|: ||:   ..:.:...:|.|.            .||..|:.:....
 Worm     3 AIIVLVVLFATIAGYFKWIH-TYW---RRRGISGPEGLPF------------IGNYYDLADVNKP 51

  Fly    69 SVFNFVRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVF----------QSTKLITKNVVYELI 123
            ..: .:.:.|.|. |:.:.:|....|:..|...:..:|:|          :||..|..|:.....
 Worm    52 RGY-LIHKWTQKF-GKVFGYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKSTNHIHGNLECSKS 114

  Fly   124 RPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE-LELNQVI 187
            .|.:  .|..|...:|...|...:|.|....|:....:.::.....::::.|:.|.: ..::...
 Worm   115 EPRI--NLFTSRGARWKRLRALASPGFSVKALKQVHDVMEDSAINMVDLMAKHEDGKPFNIHAYF 177

  Fly   188 PPFTLNNICETALGVKLDDM--SEGNEYRKAI----HAI-----------EEVLIQRVCNPLMYY 235
            ..||.:.|...|:|....::  :.|.|..|:|    |.:           .|.|::|     |:|
 Worm   178 QEFTYDVISRLAMGQPNSELFNNSGVEIVKSIFMRTHRVLPWYFTVLFPQFEHLVKR-----MFY 237

  Fly   236 NWYFFVYGDYRKHLQNLRIVHDFSSRIIERKRQQ---FQQKQLGEVDEFGRKQRYAMLDTLLAAE 297
            |......||..|.|  |.......|||.||:...   |:..:...:|.|.......:.|....:.
 Worm   238 NHAAVQGGDIEKLL--LICKKTVESRIQEREENAKLGFENAENDFIDMFLNYYSEQVEDIEFGST 300

  Fly   298 ADGQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQF 362
            .:.::..:.:......|:..|:|||:..|.:...:||.|.:..|...|||:.: ..|:::|....
 Worm   301 VEKKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMKLAQEEVDTV-VGSENVSYDDM 364

  Fly   363 NKLVYLECVIKESLRMFPSVPF-IGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHF-PKPDL 425
            .||.||:.|::||||::|...| ..|:||:.|.:..:.:.|..:|...:..:.|....: ...|.
 Worm   365 TKLKYLDAVVRESLRLYPVAWFACSRECVKPTTLGDIYIDKGVKIEADVMSLHRSKEIWGENADD 429

  Fly   426 FQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLEDLTFEN 490
            |.|:|:|..:  :||..:::||.||.|.|:|.:..:.|.|..||.::|.:.|:...:.|......
 Worm   430 FVPERWLEPS--SRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRYDLVAGVETEKELNIL 492

  Fly   491 GIVLRTQENIKVKLSKRV 508
            |....:.|.:.:.|..|:
 Worm   493 GCTTTSPEAVTLYLKPRI 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	106/451 (24%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	106/450 (24%)