Protein Alignment Cyp4ac1 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 547
• Identity: 155/547 - (28%)
• Similarity: 261/547 - (47%)
• Gaps: 105/547 - (19%)

  Fly     6 LGIPILLAVLTLLLK----HINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNL------ 60
            |.:..:|::|.||.|    ::::.: :||.|::.    .||        |....||:.:
Mouse    19 LQVASVLSLLLLLFKTAQLYLHRQW-LLSSTQQF----PSP--------PSHWLFGHKILKDQDL 70

  Fly    61 -DIL----NFTPASVFNFVRESTAKAKGQNYLW-----YFLYAPMYNVVRPEEAEEVFQSTKLI- 114
             |||    ||..|.              ..:||     ..:|.|.|              .|||
Mouse    71 QDILTRIKNFPSAC--------------PQWLWGSKVRIQVYDPDY--------------MKLIL 107

  Fly   115 -----TKNVVYELIRPFLGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLE 174
                 ..:..|..:.|::|.|||:.....|...|:.||||||:::|:.:..|..:.....|:..|
Mouse   108 GRSDPKAHGSYRFLAPWIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWE 172

  Fly   175 K--NLDAELELNQVIPPFTLNNICETAL----GVKLDDMSEGNEYRKAIHAIEE---VLIQRVCN 230
            :  ..|:.||:.|.|...||:.|.:.|.    .|:||     .:|:..|.|:|:   :...||.|
Mouse   173 QIVGQDSTLEIFQHITLMTLDTIMKCAFSHEGSVQLD-----RKYKSYIQAVEDLNNLFFLRVRN 232

  Fly   231 PLMYYNWYFFVYGD--YRKH----LQN--LRIVHDFSSRIIERKRQQFQQKQLGEVDEFGRKQRY 287
                    .|...|  ||..    |.|  .::.||.:.::|:.:|.|.|.::  |:::..:|:|.
Mouse   233 --------IFHQNDIIYRVSSNGCLANSACQLAHDHTDQVIKSRRSQLQDEE--ELEKLKKKRRL 287

  Fly   288 AMLDTLLAAEADG--QIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENL 350
            ..||.||.|..:.  .:..:.:..||:||||||:|||::.:.:....||.:.:.|::|.:|:::|
Mouse   288 DFLDILLFARMENGKSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSL 352

  Fly   351 PEDSDDISMFQFNKLVYLECVIKESLRMFPSVPFIGRQCVEE-TVVNGMVMPKDTQISIHIYDIM 414
            ..|...|:....:|:.|....|||:||::|.||.:.|:.... |..:|..:||...:.:..|.:.
Mouse   353 LGDGASITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPKGIHVMLSFYGLH 417

  Fly   415 RDPRHFPKPDLFQPDRFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLP 479
            .:|..:|.|::|.|.||.|.:  :||..:::|||.|.|||||::||:.|:||.:|..:..|:|||
Mouse   418 HNPTVWPNPEVFDPSRFAPGS--SRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLP 480

  Fly   480 ATQLEDLTFENGIVLRTQENIKVKLSK 506
            ......:.... |||:::..|.:.|.|
Mouse   481 DPTRVPIPIPR-IVLKSKNGIHLHLKK 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	133/449 (30%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	139/478 (29%)