Protein Alignment Cyp4ac1 and Cyp3a16

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031846.2
• Gene: Cyp3a16 / 13114
• MGIID: 106099
• Length: 504
• Species: Mus musculus
• Alignment Length: 528
• Identity: 134/528 - (25%)
• Similarity: 247/528 - (46%)
• Gaps: 73/528 - (13%)

  Fly    10 ILLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPASVFNFV 74
            :|||::.:||      |...:.|..:..:.|.|....:..:.         .:||:. ..::.|.
Mouse    13 VLLAIILVLL------YRYGTCTHGLFKKQGIPGPKPLPFLG---------TVLNYY-KGLWKFD 61

  Fly    75 RESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNV--VYELIRPFLGDGLL----- 132
            .|...| .|:.:..:....|::.:..||..:.|      :.|..  |:...:.|...|::
Mouse    62 MECYEK-YGKTWGLFDGQIPLFVITDPETIKNV------LVKECFSVFTNRQDFFPVGIMSKSIS 119

  Fly   133 ISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAELE------LNQVIPPFT 191
            ::.|.:|...|..|:|.|....|:....:.::    :.::|.|.|..|.|      :..|:..::
Mouse   120 LAKDEEWKRYRALLSPTFTSGNLKEMFPVIEQ----YGDILVKYLRQEAEKGKPVAVKDVLGAYS 180

  Fly   192 LNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYF-FVYGDYRKHLQNLRIV 255
            ::.|..|..||.:|.::  |.....:...::||.....:||......| |:...|  .:.|:.:.
Mouse   181 MDVIISTTFGVNIDSLN--NPEDPFVENAKKVLRFDYFDPLSLSVALFPFLTPIY--EMLNICMF 241

  Fly   256 H----DFSSRIIERKRQ-QFQQKQLGEVDEFGRKQRYAMLDTLLAAEADGQIDHQGICD-EVNT- 313
            .    :|..:.::|..: :...||...||..     |.|::..  .::..:..|:.:.: |:..
Mouse   242 PKDSIEFFKKFVDRMTENRLDSKQKHRVDFI-----YLMMEAY--NKSKDKDSHKALSEIEITAQ 299

  Fly   314 ---FMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEV-ENLPEDS----DDISMFQFNKLVYLEC 370
               |:|.||:|||:.|.||:..||.|.|:|||..||: |.||..:    |.:...:     ||:.
Mouse   300 SIIFIFAGYETTSSILSFTVYSLATHPDIQKKLQEEIDEALPNKAPPTYDTVMAME-----YLDM 359

  Fly   371 VIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPEN 435
            |:.|:||::|....:.|.|.::..:||:.:||.:.:.|..|.:..||:|:|:|:.|||:||..||
Mouse   360 VLNETLRLYPITNRLQRVCKKDVEINGIYIPKGSTVIIPSYVLHHDPQHWPEPEEFQPERFSKEN 424

  Fly   436 TVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLE-DLTFENGIVLRTQEN 499
            ..:..|:.|:||..|.|||||.:||::.||:.|..|::||...|..:.: .|.....::|:..:.
Mouse   425 KGSIDPYVYLPFGNGPRNCIGMRFALMNMKLALIKVLQNFSFQPCKETQIPLKLSRELLLQPVKP 489

  Fly   500 IKVKLSKR 507
            |.:|:..|
Mouse   490 IVLKVVPR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	118/448 (26%)
Cyp3a16	NP_031846.2	CYP3A	67..493	CDD:410743	119/452 (26%)