Protein Alignment Cyp4ac1 and Cyp19a1

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_031836.1
• Gene: Cyp19a1 / 13075
• MGIID: 88587
• Length: 503
• Species: Mus musculus
• Alignment Length: 522
• Identity: 125/522 - (23%)
• Similarity: 229/522 - (43%)
• Gaps: 88/522 - (16%)

  Fly    41 SPLESKVAIMPGKTRFGNNLDILNFTPASVFNFVRESTAKAKGQNY-------------LWYFL- 91
            :|::..|.||..:|...:.:.:|......:..:..||::...|..|             ||..:
Mouse     7 NPMQYNVTIMVPETVTVSAMPLLLIMGLLLLIWNCESSSSIPGPGYCLGIGPLISHGRFLWMGIG 71

  Fly    92 -----YAPMYNV-----VRPEEAEEVFQSTKL--ITKNVVYELIRPF--------LG---DGLLI 133
                 |..||..     :..||...:.:|:.:  :.|:..|  |..|        :|   :|::.
Mouse    72 SACNYYNKMYGEFMRVWISGEETLIISKSSSMFHVMKHSHY--ISRFGSKRGLQCIGMHENGIIF 134

  Fly   134 STDHK-WHSRR----KALT-PAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE-----LELNQVI 187
            :.:.. |.:.|    |||| |.     |...:.:..|..|:.|:.|.:..|..     |.|.:.|
Mouse   135 NNNPSLWRTIRPFFMKALTGPG-----LVRMVEVCVESIKQHLDRLGEVTDTSGYVDVLTLMRHI 194

  Fly   188 PPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYFFVYGDYRKHLQNL 252
            ...|.|.:   .||:.||:.:...:.:...:|.:.:||:.        |.:|.:...|||:.:::
Mouse   195 MLDTSNML---FLGIPLDESAIVKKIQGYFNAWQALLIKP--------NIFFKISWLYRKYERSV 248

  Fly   253 RIVHDFSSRIIERKRQQFQ-QKQLGEVDEFGRKQRYAMLDTLLAAEADGQIDHQGICDEVNTFMF 316
            :.:.|..:.::|:||.:.. .::|.:..:|.        ..|:.||..|.:..:.:...:...:.
Mouse   249 KDLKDEIAVLVEKKRHKVSTAEKLEDCMDFA--------TDLIFAERRGDLTKENVNQCILEMLI 305

  Fly   317 EGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQFNKLVYLECVIKESLRMFPS 381
            ...||.|..|.|.||::|.:.:|:....:|:..:..|. ||.:.....|..:|..|.||:|..|.
Mouse   306 AAPDTMSVTLYFMLLLVAEYPEVEAAILKEIHTVVGDR-DIKIEDIQNLKVVENFINESMRYQPV 369

  Fly   382 VPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPDRFLPENTVNRHPFAYV- 445
            |..:.|:.:|:.|::|..:.|.|.|.::| ..|....:||||:.|..:.|  |..|   |:.|.
Mouse   370 VDLVMRRALEDDVIDGYPVKKGTNIILNI-GRMHRLEYFPKPNEFTLENF--EKNV---PYRYFQ 428

  Fly   446 PFSAGQRNCIGQKFAILEMKVLLAAVIRNF--KLLPATQLEDLTFENGIVLRTQEN---IKVKLS 505
            ||..|.|.|.|:..|::.|||:|..::|.|  |.|....:|::..:|.:.|...|:   :::..|
Mouse   429 PFGFGPRGCAGKYIAMVMMKVVLVTLLRRFQVKTLQKRCIENIPKKNDLSLHPNEDRHLVEIIFS 493

  Fly   506 KR 507
            .|
Mouse   494 PR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	115/473 (24%)
Cyp19a1	NP_031836.1	CYP19A1	72..485	CDD:410709	111/445 (25%)