Protein Alignment Cyp4ac1 and Cyp3a59

DIOPT Version :10

• Sequence 1: NP_608916.1
• Gene: Cyp4ac1 / 33754
• FlyBaseID: FBgn0031693
• Length: 509
• Species: Drosophila melanogaster
• Sequence 2: NP_001098630.1
• Gene: Cyp3a59 / 100041449
• MGIID: 3769707
• Length: 503
• Species: Mus musculus
• Alignment Length: 536
• Identity: 135/536 - (25%)
• Similarity: 242/536 - (45%)
• Gaps: 87/536 - (16%)

  Fly    11 LLAVLTLLLKHINKTYFILSLTKRVRTEDGSPLESKVAIMPGKTRFGNNLDILNFTPASVFNF-- 73
            :|.|.:|:..:|..|| ...|.|::......||          ..||           ::||:
Mouse    13 VLLVTSLVFFYIYGTY-SHGLFKKLGIPGPKPL----------PLFG-----------TIFNYFD 55

  Fly    74 ----VRESTAKAKGQNYLWYFLYAPMYNVVRPEEAEEVFQSTKLITKNVVYELI--RP------F 126
                ..|...|..|:.:.:|....|:..::.||       ..|::.....|.:.  ||      |
Mouse    56 GMWKFDEDCYKKYGKIWGFYVGPKPILAIMDPE-------IIKIVLVKECYSVFTNRPTLGPVGF 113

  Fly   127 LGDGLLISTDHKWHSRRKALTPAFHFNVLQSFLGIFKEECKKFLNVLEKNLDAE------LELNQ 185
            |...:.||.|.:|...|..|:|.|....|:....|.::    :.::|.:||..|      :.:..
Mouse   114 LKKSITISEDEEWKRLRTLLSPTFTSGKLKEMFPIMRQ----YGDILVRNLRREEEKGEPINMKD 174

  Fly   186 VIPPFTLNNICETALGVKLDDMSEGNEYRKAIHAIEEVLIQRVCNPLMYYNWYF-FVYGDYRKHL 249
            :...::::.|..|:.||.:|.::  |.....:...:::|..::.:|.:.....| |:...|  .:
Mouse   175 IFGAYSMDVITGTSFGVNIDSLN--NPQNPFVQKTKKILKFKIFDPFLLSTILFPFLTPIY--EM 235

  Fly   250 QNLRIV----HDFSSRIIER-KRQQFQQKQLGEVD----------EFGRKQRYAMLDTLLAAEAD 299
            .||.|.    .:|..:.::| |:::...||...||          ..|::.:.|:.|..:||:|
Mouse   236 LNLSIFPRDSMNFFKKFVKRMKKERLASKQKNRVDFLQLMMNTQNSKGQESQKALSDLEMAAQA- 299

  Fly   300 GQIDHQGICDEVNTFMFEGYDTTSTCLIFTLLMLALHEDVQKKCYEEVENLPEDSDDISMFQFNK 364
                        ..|:|.|||.|||.:...:..||.|.|||||..:|::....:...::......
Mouse   300 ------------VIFIFGGYDATSTSISLIMYELATHPDVQKKLQDEIDRTLPNKAPVTYDALMD 352

  Fly   365 LVYLECVIKESLRMFPSVPFIGRQCVEETVVNGMVMPKDTQISIHIYDIMRDPRHFPKPDLFQPD 429
            :.||:.|:.||||::|:...:.|...::..:||:.:||.|.:.|.||.:.|:|.::|:|..|.|.
Mouse   353 MEYLDMVVNESLRLYPTAIRLERVSKKDVEINGVFIPKGTVVMIPIYPLHRNPEYWPEPQEFCPG 417

  Fly   430 RFLPENTVNRHPFAYVPFSAGQRNCIGQKFAILEMKVLLAAVIRNFKLLPATQLE-DLTFENGIV 493
            ||..||..|..|:.|:||..|.|||:..:||::.||:.:..|::||.:.|..:.: .|......|
Mouse   418 RFSKENEGNIDPYIYMPFGNGPRNCLDMRFALISMKLAVIGVLQNFTVQPCEETQIPLKISREPV 482

  Fly   494 LRTQENIKVKLSKRVK 509
            .:.::.|.:|:..|.|
Mouse   483 FQPEKPIILKVVSRDK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4ac1	NP_608916.1	CYP4	83..502	CDD:410721	116/449 (26%)
Cyp3a59	NP_001098630.1	CYP3A	67..492	CDD:410743	116/452 (26%)