Protein Alignment tkv and tgfbr2l

DIOPT Version :10

• Sequence 1: NP_787990.1
• Gene: tkv / 33753
• FlyBaseID: FBgn0003716
• Length: 575
• Species: Drosophila melanogaster
• Sequence 2: XP_688938.2
• Gene: tgfbr2l / 560446
• ZFINID: ZDB-GENE-081105-143
• Length: 590
• Species: Danio rerio
• Alignment Length: 538
• Identity: 161/538 - (29%)
• Similarity: 241/538 - (44%)
• Gaps: 106/538 - (19%)

  Fly    80 SLTCYCDGS---CPDNVSNGTCETRPGGSCFSAVQQLYDETTGMYEEE------RTYGCMPPED- 134
            :|..:||.|   |.|||....|...  ..||.|    .:....:::::      ||. |..|:.
Zfish    28 NLCKWCDHSSPVCEDNVCMSNCSLT--SYCFLA----EEVCVAIWKKDNVSVSVRTL-CYDPQHM 85

  Fly   135 -------NGGFLMCKVAAVPHLHGKNIVC-CDKEDFCNRDLYPTYTPKLTTPAPDLPVSSESLHT 191
                   |.....|.::..|...|...:| |..:..||..|.....|.          ....|.:
Zfish    86 LENIMLANYSSKECLMSPHPSEDGLLFICSCVGDQECNDRLIFDKGPN----------GFSKLKS 140

  Fly   192 LAVFGSIIISL--SVFMLIVASLCFTYKRREKLRKQPRLINSMCNSQLSPLS---QLVEQSSGSG 251
            ..|...::|||  .:.:.::|::.|...|..:..|:|:        :..|..   |.::.:.|..
Zfish   141 KDVIPVVVISLVPPLLVAVIATMAFYLYRTRQPGKKPK--------EWGPRRTHYQSLDPAEGQA 197

  Fly   252 SGLPLLVQR-------------TIAKQ---------IQMVRLVGKGRYGEVWLAK------WRDE 288
            :|:....:|             |.|..         ||:..||||||:.|||.|:      .:.|
Zfish   198 NGIDFSAKRPSLSDDINSEMSSTCANNLNHNTEQLPIQLEALVGKGRFAEVWRARLSHNESGQYE 262

  Fly   289 RVAVKTFFTTEEASWFRETEIYQTVLMRHDNILGFIAADIKGNGSWT---QMLLITDYHEMGSLH 350
            .||||.|...|.:||..|..|:....::|:|::.|:.|:.:|..|.|   |..||..|:.||:|.
Zfish   263 TVAVKIFPAVEYSSWCNERAIFSDANLKHENVVQFLTAEERGGTSATSQRQYWLIMAYYNMGNLQ 327

  Fly   351 DYLSMSVINPQKLQLLAFSLASGLAHLHDEIFGTP---GKPAIAHRDIKSKNILVKRNGQCAIAD 412
            |:|..:::...:|..||.|:|.||||||.:.  ||   .|..|||||:||.||::|...:|.:.|
Zfish   328 DFLVGNILTWAELCSLAGSVARGLAHLHSDT--TPCGIQKVPIAHRDLKSSNIVLKNQSECVLCD 390

  Fly   413 FGLAVKYNSELDVIHIAQNPRVGTRRYMAPEVLSQQLDPKQFEEFKRADMYSVGLVLWEMTRRC- 476
            ||||::.:..|.|...|.:.:|||.||||||||..:::.:..|.||:.|:||:.||:|||..||
Zfish   391 FGLALRLDLSLTVDDFANSGQVGTARYMAPEVLESRVNLEDLESFKQIDIYSMALVMWEMVSRCD 455

  Fly   477 -------YTPVSGTKTTTCEDYALPYHDVVPSDPTFEDMHAVVCVKGFRPPIPSRWQEDDVLATV 534
                   |.|..|:|  .||            .|..:.|..:|.....||.||..|.....:..:
Zfish   456 VIGEVKSYEPPFGSK--VCE------------QPCVDSMRDLVLRDRGRPDIPDSWTTHSGMQLL 506

  Fly   535 SKIMQECWHPNPTVRLTA 552
            ...:.|||..:|..||||
Zfish   507 CATITECWDHDPEARLTA 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tkv	NP_787990.1	TFP_LU_ECD_Tkv	81..169	CDD:467125	25/105 (24%)
		GS	238..266	CDD:197743	7/52 (13%)
		STKc_BMPR1	270..562	CDD:271046	116/303 (38%)
tgfbr2l	XP_688938.2	ecTbetaR2	28..131	CDD:462632	25/109 (23%)
		STKc_TGFbR2_like	238..535	CDD:270957	116/303 (38%)